ArticleJournal of biomedical optics2021
Estimation of diffuse Cherenkov optical emission from external beam radiation build-up in tissue.
Article in Journal of biomedical optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Assessment of Linac photon dose delivery on Cherenkov production.Physics and imaging in radiation oncology · 2026Article
- Cherenkov emission in realistic optical body phantoms to study effects of skin tone on imaging delivery technique.Physics in medicine and biology · 2025Article
- Hybrid Monte Carlo model for efficient tissue Cherenkov emission estimation to assess changes from beam size, energy and incidence.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025Article
- Cherenkov Imaged Bio-Morphological Features Verify Patient Positioning With Deformable Tissue Translocation in Breast Radiation Therapy.Advances in radiation oncology · 2025Article
- Innovative approaches in precision radiation oncology: advanced imaging technologies and challenges which shape the future of radiation therapy.Frontiers in medicine · 2025Review
- Color-resolved Cherenkov imaging allows for differential signal detection in blood and melanin content.Journal of biomedical optics · 2023Article
- Performance comparison of quantitative metrics for analysis of in vivo Cherenkov imaging incident detection during radiotherapy.The British journal of radiology · 2022Article
- Comparison of surface dose during whole breast radiation therapy on Halcyon and TrueBeam using Cherenkov imaging.Proceedings of SPIE--the International Society for Optical EngineeringArticle
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Authors and funding
7 authors.
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Abstract
significanceOptical imaging of Cherenkov emission during radiation therapy could be used to verify dose delivery in real-time if a more comprehensive quantitative understanding of the factors affecting emission intensity could be developed.
aimThis study aims to explore the change in diffuse Cherenkov emission intensity with x-ray beam energy from irradiated tissue, both theoretically and experimentally. APPROACH: Derivation of the emitted Cherenkov signal was achieved using diffusion theory, and experimental studies with 6 to 18 MV energy x-rays were performed in tissue phantoms to confirm the model predictions as related to the radiation build-up factor with depth into tissue.
resultsIrradiation at lower x-ray energies results in a greater surface dose and higher build-up slope, which results in a ∼46 % greater diffusely emitted Cherenkov signal per unit dose at 6 MV relative to 18 MV x-rays. However, this phenomenon competes with a decrease in signal from less Cherenkov photons being generated at lower energies, a ∼44 % reduction at 6 versus 18 MV. The result is an emitted Cherenkov signal that is nearly constant with beam energy.
conclusionsThis study explains why the observed Cherenkov emission from tissue is not a strong function of beam energy, despite the known strong correlation between Cherenkov intensity and particle energy in the absence of build-up and scattering effects.
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