ArticleJournal of magnetic resonance imaging : JMRI2022
Hepatic Iron Quantification Using a Free-Breathing 3D Radial Gradient Echo Technique and Validation With a 2D Biopsy-Calibrated R
Article in Journal of magnetic resonance imaging : JMRI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Best practices for pediatric liver MRI: guidelines from members of the Society for Pediatric Radiology Magnetic Resonance and Abdominal Imaging Committees.Pediatric radiology · 2025Guideline
- Generalized U-Net for automatic liver segmentation and R2* estimation for assessment of iron overload using MRI.BMC medical imaging · 2026Article
- Accelerated free-breathing volumetric liver proton density fat fraction (PDFF) andMagma (New York, N.Y.) · 2026Article
- State-of-the-Art Quantification of Liver Iron With MRI-Vendor Implementation and Available Tools.Journal of magnetic resonance imaging : JMRI · 2025Review
- Practical approach to quantitative liver and pancreas MRI in children.Pediatric radiology · 2025Review
- Free-breathing MRI techniques for fat and RMagma (New York, N.Y.) · 2024Review
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundHepatic iron content (HIC) is an important parameter for the management of iron overload. Non-invasive HIC assessment is often performed using biopsy-calibrated two-dimensional breath-hold Cartesian gradient echo (2D BH GRE) R PURPOSE: To evaluate the performance of a 3D FB rGRE and validate its R STUDY TYPE: Retrospective. SUBJECTS: Twenty-nine patients with hepatic iron overload (22 females, median age: 15 [5-25] years). FIELD STRENGTH/SEQUENCE: Three-dimensional radial and 2D and 3D Cartesian multi-echo GRE at 1.5 T. ASSESSMENT: R STATISTICAL TESTS: Inter- and intra-observer reproducibility was assessed using Bland-Altman and intraclass correlation coefficient (ICC). Linear regression and Bland-Altman analysis were performed to compare R
resultsThe mean biases and ICC for inter- and intra-observer reproducibility were close to 0% and >0.99, respectively for both R DATA
conclusionFree-breathing 3D radial GRE is a viable alternative in non-breath-hold patients for accurate HIC estimation. LEVEL OF EVIDENCE: 3 TECHNICAL EFFICACY: Stage 2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.