ArticleJournal of general internal medicine2022
Perioperative Management of Buprenorphine/Naloxone in a Large, National Health Care System: a Retrospective Cohort Study.
Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Perioperative Management of Patients on Buprenorphine.Current pain and headache reports · 2026Review
- Use and Outcomes of Medication for Opioid Use Disorder Among Patients With Opioid Use Disorder Undergoing Surgery.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Experiencing Housing Instability in Rural North America and Access to Health Care and Supportive Services: A Scoping Review.Journal of health care for the poor and underserved · 2025Article
- Narrative review: Managing buprenorphine and opioid use disorder in the perioperative setting.Pain practice : the official journal of World Institute of Pain · 2025Review
- The Efficacy of Buprenorphine in Preoperative and Postoperative Patients: A Literature Review.Cureus · 2024Review
- Continuation of Buprenorphine During Hospitalization and Subsequent Retention in Therapy: an Observational Study in Veterans Administration Hospitals.Journal of general internal medicine · 2024Observational
- Case report: Successful induction of buprenorphine in medically complex patients concurrently on opioids: a case series at a tertiary care center.Frontiers in pharmacology · 2024Article
- A scoping review of surgical care for people experiencing homelessness: prevalence, access, and disparities.Canadian journal of surgery. Journal canadien de chirurgieArticle
- Post-operative pain control in patients on buprenorphine or methadone for opioid use disorder.Journal of opioid managementArticle
- "I'm Clean and Sober, But Not Necessarily Free": Perceptions of Buprenorphine Among Patients in Long-Term Treatment.Substance abuseArticle
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundMedication for opioid use disorder, including buprenorphine and methadone, is considered the gold standard treatment for opioid use disorder (OUD). As the number of patients receiving buprenorphine has grown, clinicians increasingly care for patients prescribed buprenorphine who present for surgery and require management of perioperative pain.
objectiveTo describe practice patterns of perioperative and post-surgical use of buprenorphine among patients prescribed buprenorphine for OUD who experience major surgery.
designRetrospective cohort study utilizing data from the VA Corporate Data Warehouse (CDW), a national repository of patient-level data. Data not accessible in CDW, including clinical instructions to patients to modify buprenorphine dose, were accessed via chart review.
participantsNational sample of patients receiving care through the Veterans Health Administration. MAIN MEASURES: We report descriptive statistics on the incidence of buprenorphine dose hold prior to, during, and immediately following surgery, as well as post-surgical outcomes. Multivariable logistic regression identified socio-demographic and clinical characteristics associated with perioperative hold. KEY
resultsOur final sample comprised 183 patients, the majority of whom were white and male. Most patients (66%) experienced a perioperative buprenorphine dose hold: during the pre-operative, day of surgery, and post-operative periods, 40%, 62%, and 55% of patients had buprenorphine held. Buprenorphine dose hold was less likely for patients who had experienced homelessness/housing insecurity in the year prior to surgery (aOR = 0.25; 95% CI 0.10-0.61) as well as patients residing in rural areas (aOR=0.29; 0.12-0.68). Within the 12-month period following surgery, 122 patients (67%) were retained on buprenorphine, 10 patients (5.5%) had experienced an overdose, and 15 (8.2%) had died.
conclusionsWe identified high rates of perioperative buprenorphine dose holds. As holding buprenorphine perioperatively does not align with emerging clinical recommendations and carries significant risks, educational campaigns or other provider-targeted interventions may be needed to ensure patients with OUD receive recommended care.
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