Evidence map›Paper›PMID 34545348›Full record

ArticleBrain hemorrhages2021

Neurological complications of SARS-CoV-2: A single-center case series authors.

Muhammad Hassan, Naveed Ullah Khan, Mansoor Iqbal, Zakir Jan, Haris Majid Rajput, Rebecca Susan Dewey, Mazhar Badshah

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Brain hemorrhages, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Muhammad HassanShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Naveed Ullah KhanShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Mansoor IqbalShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Zakir JanShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Haris Majid RajputShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Rebecca Susan DeweyNeuroimaging, University of Nottingham, United Kingdom.
Mazhar BadshahShaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, Pakistan.
Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology · PKUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurological manifestations of SARS-CoV-2 are wide-ranging from simple headache to severe demyelinating brain disease. This is a review of collected case reports of patients with SARS-CoV-2 with neurological manifestations presenting to the Pakistan Institute of Medical Sciences (PIMS). Neurological manifestations associated with SARS-CoV-2 such as encephalitis, acute cerebrovascular disease, encephalitis with chorea, post-COVID myositis and Guillain-Barré Syndrome (GBS) are of great concern but are often overlooked in the presence of life-threatening abnormal vital signs in severely ill SARS-CoV-2 patients. There is a need to diagnose these manifestations at the earliest opportunity to limit long-term consequences and complications. Much research is needed to explore the role of SARS-CoV-2 in causing these neurological manifestations by isolating it either from the cerebrospinal fluid (CSF) or the brain tissue of the deceased on autopsy. We also recommend exploring the risk factors that lead to the development of these neurological manifestations.

Indexed as

Covid-19EncephalitisGuillian Barre SyndromePolymyositisStroke

Identifiers

PMID34545348
PMCPMC8443530
OpenAlexW3199542428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.