Evidence map›Paper›PMID 34545167›Full record

ArticleJournal of clinical research in pediatric endocrinology2022

Mutation Screening and Functional Study of

Chang-Run Zhang, Yuan-Ping Shi, Cao-Xu Zhang, Feng Sun, Wen-Jiao Zhu, Rui-Jia Zhang, Ya Fang, Qian-Yue Zhang, Chen-Yan Yan, Ying-Xia Ying and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Chang-Run ZhangThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0001-6237-6220
Yuan-Ping ShiThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0001-7038-9283
Cao-Xu ZhangThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0001-7653-0225
Feng SunThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0001-7079-9741
Wen-Jiao ZhuThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0002-2970-1412
Rui-Jia ZhangThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0002-4485-1398
Ya FangThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0003-4023-1586
Qian-Yue ZhangThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0003-3691-5117
Chen-Yan YanThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0002-0328-4964
Ying-Xia YingThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0003-4098-5003
Shuang-Xia ZhaoThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0001-7203-3408
Huai-Dong SongThe Core Laboratory in Medical Center of Clinical Research, Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, ChinaORCID 0000-0002-9609-5803
Shanghai Jiao Tong University · CNShanghai Ninth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Defects in the human solute carrier family 26 member 4 ( Methods: Patients with primary CH were screened for 21 CH candidate genes mutations by targeted next-generation sequencing. All the exons and exon-intron boundaries of Results: Among 273 patients with CH, seven distinct Conclusion: The prevalence of

Indexed as

Congenital HypothyroidismHearing Loss, SensorineuralSulfate TransportersAsian PeopleChinaHeterozygoteHumansMutationSLC26A4 protein, humanSulfate Transporterscell locationCongenital hypothyroidismion transportnext-generation sequencingSLC26A4

Identifiers

PMID34545167
PMCPMC8900076
OpenAlexW3199435154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.