Evidence map›Paper›PMID 34545006›Full record

ArticleJournal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi2021

Myorelaxant and antispasmodic effect of an aqueous extract of Artemisia campestris L. via calcium channel blocking and anticholinergic pathways.

Mohamed Marghich, Ouafa Amrani, Hassane Mekhfi, Abderrahim Ziyyat, Mohamed Bnouham, Mohammed Aziz

Open access · diamondAbstract read
In one paragraph

Article in Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mohamed MarghichLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
Ouafa AmraniLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
Hassane MekhfiLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
Abderrahim ZiyyatLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
Mohamed BnouhamLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
Mohammed AzizLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences, Mohamed the First University, Boulevard Mohamed VI; BP: 717; 60000, Oujda, Morocco.
BP (United Kingdom) · GBMohamed I University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal spasms are violent contractions that occur in the intestine, which cause discomfort to people who have them. Medicinal plants are widely used in traditional Moroccan medicine to treat these problems, among these being Artemisia campestris L. This study aims to evaluate the relaxant and antispasmodic effects of an aqueous extract of this plant (ACAE). It was performed in vitro on isolated segments of both isolated rat and rabbit jejunum mounted in an organ bath and tension recordings made via an isotonic transducer. ACAE caused a myorelaxant effect on baseline rabbit jejunum contractions in a dose-dependent and reversible manner with an IC

Indexed as

ArtemisiaParasympatholyticsAnimalsCalcium ChannelsCholinergic AntagonistsPlant ExtractsRabbitsRatsCalcium ChannelsCholinergic AntagonistsParasympatholyticsPlant ExtractsanticholinergicantispasmodicArtemisia campestris L.calcium channel blockingjejunum

Identifiers

PMID34545006
PMCPMC8443802
OpenAlexW3199051252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.