Evidence map›Paper›PMID 34544864›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Juvenile hormone signaling promotes ovulation and maintains egg shape by inducing expression of extracellular matrix genes.

Wei Luo, Suning Liu, Wenqiang Zhang, Liu Yang, Jianhua Huang, Shutang Zhou, Qili Feng, Subba Reddy Palli, Jian Wang, Siegfried Roth and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Ubiquitination plays a key role in an insecticide resistance fitness cost.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  5. Single-cell transcriptomics of theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Female membrane proteins regulate postmating ovulation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. 20E-inducedProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. A hormone-to-neuropeptide pathway inhibits sexual receptivity in immatureProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Regional specialization, polyploidy, and seminal fluid transcripts in theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Actomyosin contraction in the follicular epithelium provides the major mechanical force for follicle rupture duringProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. GPCR-MAPK signaling pathways underpin fitness trade-offs in whitefly.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Wei LuoGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0002-0698-3066
Suning LiuGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China; lisheng@scnu.edu.cn liusuning@m.scnu.edu.cn.ORCID 0000-0002-7738-6218
Wenqiang ZhangGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0002-9711-4025
Liu YangGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0002-0414-4293
Jianhua HuangInstitute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-6509-1765
Shutang ZhouKey Laboratory of Plant Stress Biology, State Key Laboratory of Cotton Biology, School of Life Sciences, Henan University, Kaifeng 475004, China.
Qili FengGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0003-2105-6831
Subba Reddy PalliDepartment of Entomology, College of Agriculture, Food, and Environment, University of Kentucky, Lexington, KY 40546.ORCID 0000-0002-0873-3247
Jian WangDepartment of Entomology, University of Maryland, College Park, MD 20742.
Siegfried RothInstitute for Zoology, University of Cologne, D-50674 Cologne, Germany.ORCID 0000-0001-5772-3558
Sheng LiGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China; lisheng@scnu.edu.cn liusuning@m.scnu.edu.cn.ORCID 0000-0002-4217-2367
South China Normal University · CNHenan University · CNUniversity of Cologne · DEUniversity of Kentucky · USUniversity of Maryland, College Park · USZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well documented that the juvenile hormone (JH) can function as a gonadotropic hormone that stimulates vitellogenesis by activating the production and uptake of vitellogenin in insects. Here, we describe a phenotype associated with mutations in the

Indexed as

OogenesisOvulationAnimalsBasic Helix-Loop-Helix ProteinsCollagen Type IVDrosophila melanogasterDrosophila ProteinsExtracellular MatrixExtracellular Matrix ProteinsFemaleJuvenile HormonesLamininMutationOocytesTranscription FactorsVitellogenesisBasic Helix-Loop-Helix ProteinsCollagen Type IVDrosophila ProteinsExtracellular Matrix Proteinsgce protein, DrosophilaJuvenile HormonesLamininMET protein, DrosophilaTranscription FactorsVitellogeninscollagen IVegg chamber elongationlamininovarian contractionvisceral muscle

Identifiers

PMID34544864
PMCPMC8488625
OpenAlexW3199707678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.