Evidence map›Paper›PMID 34544823›Full record

ArticleRMD open2021

Hyperechogenic intimal lesions and wall thickness of the temporal and facial arteries in elderly patients with arterial occlusions of the eye.

Michael Czihal, Anton Köhler, Ilaria Prearo, Ulrich Hoffmann, Hendrik Schulze-Koops, Claudia Dechant, Siegfried G Priglinger, Marc J Mackert, Christian Lottspeich

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. [Imaging of large vessel vasculitis].Zeitschrift fur Rheumatologie · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Michael CzihalDivision of Vascular Medicine, Medicial Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany michael.czihal@med.uni-muenchen.de.ORCID 0000-0003-4199-6345
Anton KöhlerDivision of Vascular Medicine, Medicial Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Ilaria PrearoDivision of Vascular Medicine, Medicial Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Ulrich HoffmannDivision of Vascular Medicine, Medicial Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Hendrik Schulze-KoopsDivision of Rheumatology and Clinical Immunology, Medical Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.ORCID 0000-0002-1681-491X
Claudia DechantDivision of Rheumatology and Clinical Immunology, Medical Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Siegfried G PriglingerDepartment of Ophthalmology, Hospital of the Ludwig Maximilians University, Munich, Germany.
Marc J MackertDepartment of Ophthalmology, Hospital of the Ludwig Maximilians University, Munich, Germany.
Christian LottspeichInterdisciplinary Sonography Center, Medical Clinic and Policlinic IV, Hospital of the Ludwig Maximilians University, Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the association of arteriosclerosis, characterised by hyperechogenic intimal lesions (HIL), with wall thickness of the temporal and facial arteries in elderly patients with ocular arterial occlusions.

methodsPatients suffering from non-arteritic ocular perfusion disorders were included. High-resolution compression sonography (18 MHz) images of the temporal arteries (frontal and parietal branch at the upper margin of the auricle) and facial arteries (at the crossing point of the artery over the mandible) were analysed for the presence of HIL (grade 0: absent; grade 1: moderate; grade 2: severe). Characteristics of patients with and without evidence of HIL >grade 1 were compared.

resultsIn total, 330 cranial artery segments of 55 patients were analysed. HIL ≥grade 1 was present in 13.0% of all artery segments and in 38.1% of all patients. Patients with HIL ≥grade 1 in at least one arterial segment displayed significantly increased maximum wall thickness of the temporal arteries (0.62±0.23 mm vs 0.50±0.13 mm; p<0.01) and facial arteries (0.71±0.20 mm vs 0.54±0.19 mm; p=0.01). Patients with at least one temporal or facial artery segment with HIL were older, more often male and more frequently suffered from diabetes mellitus.

conclusionThe presence of HIL goes along with a significantly increased wall thickness of the temporal and facial arteries. These findings should be considered when interpreting the results of sonography of the cranial arteries in the diagnostic workup of suspected giant cell arteritis.

Indexed as

Giant Cell ArteritisTemporal ArteriesAgedArteriesHumansMaleUltrasonographyatherosclerosisgiant cell arteritissystemic vasculitisultrasonography

Identifiers

PMID34544823
PMCPMC8454441
OpenAlexW3201039130

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.