ArticleNeurology2021
Epidemiology, Clinical Features, and Outcome in a Cohort of Adolescents With Cerebral Venous Thrombosis.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in Neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Safety and Efficacy of Rivaroxaban Versus Warfarin in Cerebral Venous Thrombosis: A Comprehensive Meta-Analysis.Neurology international · 2025Review
- Progressive Superior Sagittal Sinus Thrombosis Successfully Treated With Angioplasty: A Case Report.Cureus · 2025Article
- Response to "Critical Insights on 'Early Versus Late Initiation of Endovascular Therapy in Patients with Severe Cerebral Venous Sinus Thrombosis' by Bücke et al."Neurocritical care · 2024Article
- Early Versus Late Initiation of Endovascular Therapy in Patients with Severe Cerebral Venous Sinus Thrombosis.Neurocritical care · 2024Article
- Cerebral venous thrombosis in elderly patients.European journal of neurology · 2024Article
- Current understanding of stroke and stroke mimics in adolescents and young adults: a narrative review.International journal of emergency medicine · 2024Review
- Cortical vein involvement and its influence in a cohort of adolescents with cerebral venous thrombosis.Thrombosis journal · 2023Article
- Endovascular Treatment of Intracranial Vein and Venous Sinus Thrombosis-A Systematic Review.Journal of clinical medicine · 2022Review
- Predictive Factors for Early-Onset Seizures in Patients With Cerebral Venous Sinus Thrombosis.Frontiers in neurology · 2022Article
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Authors and funding
13 authors at 1 institution in 1 country.
Julia DevianneFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Nicolas LegrisFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Isabelle CrassardFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Celine BellesmeFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Yannick BejotFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Celine GuidouxFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Fernando PicoFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
David GermanaudFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Michael ObadiaFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Diana RodriguezFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.
Philippe TuppinFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.ORCID 0000-0001-5698-9215
Manoelle KossorotoffFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France.ORCID 0000-0002-0813-9045
Christian DenierFrom the Stroke Units and Departments of Neurology of Hôpital Bicêtre (J.D., N.L., C.D.), Le Kremlin Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), and Paris Saclay University; Hôpital Lariboisière (I.C.), AP-HP, Paris; Pediatric Neurology and Stroke Unit (C.B.), AP-HP, Hôpital Bicêtre; University Région Bourgogne (Y.B.), Hôpital de Dijon; Hôpital Bichat (C.G.), AP-HP, Paris; Hôpital André Mignot (F.P.), Versailles; Hôpital Armand Trousseau (D.R.), AP-HP; Hôpital Fondation Rothschild (M.O.); Hôpital Robert Debré (D.G.), AP-HP; French National Health Insurance (CNAM) (P.T.); and Pediatric Neurology Unit and French Center for Pediatric Stroke (M.K.), AP-HP, Hôpital Necker-Enfants malades, Paris, France. christian.denier@aphp.fr.
Université Paris-Saclay · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesWe aimed to analyze the epidemiologic, clinical, and paraclinical features of adolescents with cerebral venous thrombosis (CVT) and its therapeutic management and outcome.
methodsThis multicenter retrospective cohort included patients 10 to 18 years of age hospitalized for a first episode of CVT in 2 French regions between 1999 and 2019. The number of cases was compared to the number recorded by the French health insurance system. The CVT registry of the Lariboisière hospital allowed comparisons with adults.
resultsOne hundred two patients were included (52.9% female; median age 15.1 years). Estimated incidence was 0.37 to 0.38 per 100,000 adolescents per year; 45.5% of patients presented with focal deficits or seizures or in a coma. Male patients were younger than female patients (14.2 vs 15.6 years; DISCUSSION: CVT in adolescents is rare and complex with specific epidemiology, including differences in clinical presentation and associated conditions between sexes, and more severe outcomes than in adults. Careful specialized management and follow-up are therefore recommended.
Indexed as
Intracranial ThrombosisVenous ThrombosisAdolescentAdultFemaleHumansMaleRetrospective StudiesRisk FactorsSeizures
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