Evidence map›Paper›PMID 34544628›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2021

Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.

Siobhan C McKay, Samir Pathak, Richard J W Wilkin, Sivesh K Kamarajah, Stephen J Wigmore, Jonathan Rees, Declan F J Dunne, Giuseppe Garcea, Jawad Ahmad, Nicola de Liguori Carino and 33 more

Abstract read
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Maintaining early diagnosis of pancreatic adenocarcinoma in Japan: Local resilience against COVID-19.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Pancreas in Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
    Review
  10. Article
  11. COVID-19 and the Pancreas: A Narrative Review.Life (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Siobhan C McKayThe Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UK; Academic Department of Surgery, University of Birmingham, Birmingham, UK. Electronic address: Siobhan.mckay@uhb.nhs.uk.
Samir PathakUniversity Hospitals Bristol NHS Foundation Trust, Bristol, BS2 8HW, UK; Centre for Surgical Research, University of Bristol, Canynge Hall, 39, Whatley Road, Bristol, BS8 2PS, UK. Electronic address: drsamirpathak@gmail.com.
Richard J W WilkinAcademic Department of Surgery, University of Birmingham, Birmingham, UK. Electronic address: richardwilkin@doctors.net.uk.
Sivesh K KamarajahDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear, UK. Electronic address: siveshkk93@gmail.com.
Stephen J WigmoreDepartment of Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, EH16 4SA, UK. Electronic address: s.wigmore@ed.ac.uk.
Jonathan ReesUniversity Hospitals Bristol NHS Foundation Trust, Bristol, BS2 8HW, UK. Electronic address: Jonathan.Rees@bristol.ac.uk.
Declan F J DunneDepartment of Pancreatobiliary Surgery, Royal Liverpool University Hospital, L7 8XP, UK. Electronic address: declan.dunne@rlbuht.nhs.uk.
Giuseppe GarceaDepartment of HPB Surgery, University Hospitals of Leicester, Gwendolen Road, Leicester, LE5 4PW, UK. Electronic address: giuseppe.garcea@uhl-tr.nhs.uk.
Jawad AhmadUniversity Hospitals Coventry and Warwickshire, Clifford Bridge Rd, Coventry, CV2 2DX, UK. Electronic address: jawad.ahmad@uhcw.nhs.uk.
Nicola de Liguori CarinoDepartment of HPB Surgery, Manchester Royal Infirmary, University of Manchester, Manchester, M13 9WL, UK. Electronic address: nicola.deliguoricari0@mft.nhs.uk.
Asma SultanaDepartment of HPB Surgery, East Lancashire Teaching Hospitals NHS Trust, Haslingden Road, Blackburn, BB2 3HH, UK. Electronic address: asma.sultana@elht.nhs.uk.
Mike SilvaOxford University Hospitals NHS FT, Headley Way, Headington, Oxford, OX3 9DU, UK. Electronic address: mikesilva10@gmail.com.
Pavlos LykoudisHull University Teaching Hospitals, Hull, HU3 2JZ, UK. Electronic address: pavlos.lykoudis@hey.nhs.uk.
David NasrallaDepartment of HPB Surgery, The Royal Free Hospital, Pond Street, London, NW3 2QG, UK. Electronic address: David.nasralla@nhs.net.
James MilburnHPB Surgical Unit, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK. Electronic address: j.milburn@nhs.net.
Nehal ShahDepartment of HPB Surgery. Sheffield University Teaching Hospital. Sheffield, S5 7AU, UK. Electronic address: nehal.shah@nhs.net.
Hemant M KocherBarts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. Electronic address: h.kocher@qmul.ac.uk.
Ricky BhogalThe Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK; Institute for Cancer Research, 123 Old Brompton Road, South Kensington, London, SW7 3RP, UK. Electronic address: ricky.bhogal@rmh.nhs.uk.
Ryan D BaronDepartment of Pancreatobiliary Surgery, Royal Liverpool University Hospital, L7 8XP, UK. Electronic address: Ryan.baron@liverpoolft.nhs.uk.
Alex NavarroNottingham University Hospitals, Derby Rd, Lenton, Nottingham, NG7 2UH, UK. Electronic address: alexnavarro1978@gmail.com.
James Halle-SmithThe Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UK. Electronic address: James.Halle-Smith@uhb.nhs.uk.
Bilal Al-SarirehMorriston Hospital, Heol Maes Eglwys, Morriston, Cwmrhydyceirw, Swansea, SA6 6NL, UK. Electronic address: Bilal.al-sarireh@wales.nhs.uk.
Gourab SenDepartment of Hepatobiliary, Pancreatic and Transplant Surgery, The Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear, UK. Electronic address: gourab.sen@nhs.net.
Nigel B JamiesonWest of Scotland Pancreatic Unit, Glasgow Royal Infirmary, 84 Castle St, Glasgow, G4 0SF, UK; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, G61 1BD, UK. Electronic address: nigel.jamieson@glasgow.ac.uk.
Christopher BriggsUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK. Electronic address: christopherbriggs@nhs.net.
David StellUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK. Electronic address: David.Stell@nhs.net.
Somaiah ArooriUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK. Electronic address: Somaiah.Aroori@nhs.net.
Matthew BowlesUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK. Electronic address: Matthew.Bowles@nhs.net.
Aditya KanwarUniversity Hospitals Plymouth NHS Trust, Derriford Road, Crownhill, Plymouth, Devon, PL6 8DH, UK. Electronic address: Aditya.Kanwar@nhs.net.
Simon HarperAddenbrookes Hospital, Hills Rd, Cambridge, CB2 0QQ, UK. Electronic address: simon.harper@addenbrookes.nhs.uk.
Krishna MenonKing's College Hospital, Denmark Hill, Brixton, London, SE5 9RS, UK. Electronic address: krishna.menon@nhs.net.
Andreas PrachaliasKing's College Hospital, Denmark Hill, Brixton, London, SE5 9RS, UK. Electronic address: Andreas.Prachalias@nhs.net.
Parthi SrinivasanKing's College Hospital, Denmark Hill, Brixton, London, SE5 9RS, UK. Electronic address: Parthi.Srinivasan@nhs.net.
Adam E FramptonHPB Surgical Unit, Royal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey, GU2 7XX, UK; Department of Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7WG, UK. Electronic address: aframpton@nhs.net.
Claire JonesMater Hospital, 45-51 Crumlin Rd, Belfast, BT14 6AB, UK. Electronic address: claire.jones@belfasttrust.hscni.net.
Ali ArshadUniversity Hospital Southampton, Tremona Road, Southampton, Hampshire, SO16 6YD, UK. Electronic address: Ali.Arshad@uhs.nhs.uk.
Iain TaitWard 11, Ninewells Hospital and Medical School Dundee, DD1 9SY, UK. Electronic address: itait@nhs.net.
Duncan SpaldingDepartment HPB Surgery, Hammersmith Hospital, DuCane Road, London, W12 0HS, UK; Department of Surgery and Cancer, Imperial College London, London, UK. Electronic address: d.spalding@imperial.ac.uk.
Alastair L YoungDepartment of Pancreatic Surgery, St James's University Hospital, Leeds, LS9 7TF, UK. Electronic address: alistair.young@nhs.net.
Damien DurkinRoyal Stoke NHS Trust, Newcastle Road, Stoke-on-Trent, ST4 6QG, UK. Electronic address: ddurkin@doctors.org.uk.
Manijeh Ghods-GhorbaniAcademic Department of Surgery, University of Birmingham, Birmingham, UK. Electronic address: Manijeh.Ghods-Ghorbani@uhb.nhs.uk.
Robert P SutcliffeThe Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UK. Electronic address: robert.sutcliffe@uhb.nhs.uk.
Keith J RobertsThe Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UK. Electronic address: Keith.Roberts@uhb.nhs.uk.

Funding

Medical Research Council MR/N005872/1
6 · The paper itself

Abstract

introductionThe SARS-CoV-2 pandemic presented healthcare providers with an extreme challenge to provide cancer services. The impact upon the diagnostic and treatment capacity to treat pancreatic cancer is unclear. This study aimed to identify national variation in treatment pathways during the pandemic.

methodsA survey was distributed to all United Kingdom pancreatic specialist centres, to assess diagnostic, therapeutic and interventional services availability, and alterations in treatment pathways. A repeating methodology enabled assessment over time as the pandemic evolved.

resultsResponses were received from all 29 centres. Over the first six weeks of the pandemic, less than a quarter of centres had normal availability of diagnostic pathways and a fifth of centres had no capacity whatsoever to undertake surgery. As the pandemic progressed services have gradually improved though most centres remain constrained to some degree. One third of centres changed their standard resectable pathway from surgery-first to neoadjuvant chemotherapy. Elderly patients, and those with COPD were less likely to be offered treatment during the pandemic.

conclusionThe COVID-19 pandemic has affected the capacity of the NHS to provide diagnostic and staging investigations for pancreatic cancer. The impact of revised treatment pathways has yet to be realised.

Indexed as

COVID-19Pancreatic NeoplasmsAgedHumansPandemicsSARS-CoV-2United Kingdom

Identifiers

PMID34544628
PMCPMC7973054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.