Evidence map›Paper›PMID 34544481›Full record

ReviewRadiation oncology (London, England)2021

Patient positioning and immobilization procedures for hybrid MR-Linac systems.

Francesco Cuccia, Filippo Alongi, Claus Belka, Luca Boldrini, Juliane Hörner-Rieber, Helen McNair, Michele Rigo, Maartje Schoenmakers, Maximilian Niyazi, Judith Slagter and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  4. Patient setup variation on Elekta Unity and its impact on adaptive planning.Journal of applied clinical medical physics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Francesco CucciaAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar Di Valpolicella, VR, Italy. f.cuccia1@virgilio.it.ORCID http://orcid.org/0000-0003-0390-9511
Filippo AlongiAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar Di Valpolicella, VR, Italy.
Claus BelkaDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
Luca BoldriniRadiology, Radiation Oncology and Hematology Department, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Roma, Italy.
Juliane Hörner-RieberDepartment of Radiation Oncology, University Hospital of Heidelberg, National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg, Germany.
Helen McNairThe Royal Marsden NHS Foundation Trust, and Institute of Cancer Research Sutton, Surrey, UK.
Michele RigoAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar Di Valpolicella, VR, Italy.
Maartje SchoenmakersDepartment of Radiation Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Maximilian NiyaziDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
Judith SlagterDepartment of Radiation Oncology - Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Claudio VottaRadiology, Radiation Oncology and Hematology Department, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Roma, Italy.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
LMU Klinikum · DEOspedale Sacro Cuore Don Calabria · ITAgostino Gemelli University Polyclinic · ITHeidelberg University · DEAmsterdam University Medical Centers · NLRoyal Marsden NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hybrid magnetic resonance (MR)-guided linear accelerators represent a new horizon in the field of radiation oncology. By harnessing the favorable combination of on-board MR-imaging with the possibility to daily recalculate the treatment plan based on real-time anatomy, the accuracy in target and organs-at-risk identification is expected to be improved, with the aim to provide the best tailored treatment. To date, two main MR-linac hybrid machines are available, Elekta Unity and Viewray MRIdian. Of note, compared to conventional linacs, these devices raise practical issues due to the positioning phase for the need to include the coil in the immobilization procedure and in order to perform the best reproducible positioning, also in light of the potentially longer treatment time. Given the relative novelty of this technology, there are few literature data regarding the procedures and the workflows for patient positioning and immobilization for MR-guided daily adaptive radiotherapy. In the present narrative review, we resume the currently available literature and provide an overview of the positioning and setup procedures for all the anatomical districts for hybrid MR-linac systems.

Indexed as

Particle AcceleratorsPatient PositioningAbdominal NeoplasmsBrain NeoplasmsHead and Neck NeoplasmsHumansMagnetic Resonance ImagingNeoplasmsRadiotherapy, Image-GuidedThoracic Neoplasms

Identifiers

PMID34544481
PMCPMC8454038
OpenAlexW3199470404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.