Evidence map›Paper›PMID 34544462›Full record

ArticleSubstance abuse treatment, prevention, and policy2021

Acute Toxic Effects of the New Psychoactive Substance "Voodoo" among Patients presented to the Poison Control Center of Ain Shams University Hospitals (PCC-ASUH), Egypt, during 2017.

Rania Hussien, Maged El-Setouhy, Mohamed El Shinawi, Hazem Mohamed El-Hariri, Jon Mark Hirshon

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Article in Substance abuse treatment, prevention, and policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Rania HussienDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. raniahussien@med.asu.edu.eg.ORCID 0000-0002-9101-2474
Maged El-SetouhyDepartment of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Mohamed El ShinawiDepartment of Emergency Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Hazem Mohamed El-HaririDepartment of Community Medicine, National Research Centre, Cairo, Egypt.
Jon Mark HirshonDepartment of Emergency Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Funding

INJURY PREVENTION TRAINING IN EGYPT AND THE MIDDLE EASTD43TW007296 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI HIRSHON, JON MARK · 2005 to 2020
$3.5M
FIC NIH HHS D43 TW007296
6 · The paper itself

Abstract

backgroundVoodoo is a heterogeneous mixture of psychoactive substances that has recently grown in popularity among youth in Egypt. Patients can present with a variety of manifestations that may lead to death in some cases. This study assessed the acute toxic effects of voodoo among patients presented to the Poison Control Center of Ain Shams University Hospitals (PCC-ASUH) during a one year period.

methodsThis is a retrospective study of all patients presented with voodoo intoxication at the PCC-ASUH from 1 January 2017 to 31 December 2017. Clinical data, routine laboratory findings, and ECG results as well as duration of hospitalization and outcome were compiled from hospital records.

resultsSeventy-one voodoo intoxication cases meeting the inclusion criteria were analyzed (mean age: 25.19 ± 9.54 years, range: 15-50 years, 97.2 % male). Pulse, blood pressure, and respiratory rate were normal in more than half of all patients. Neurological abnormalities including agitation, hallucinations, disturbance of consciousness were the most frequent manifestations. Respiratory acidosis was the most common laboratory finding (54.9 %), followed by increased serum urea (43.6 %), hypokalemia (33.8 %), hyperglycemia (28.1 %), and leukocytosis (26.7 %). The most common ECG finding was sinus tachycardia (31 %), followed by QT prolongation (15.4 %). More than half of the studied patients (53.5 %) co-administered other illicit substances, most frequently cannabis and tramadol. Most patients recovered fully and were discharged, but death occurred in two cases.

conclusionsVoodoo toxicity can manifest with many presentations, hampering timely diagnosis. Clinicians should consider possible voodoo poisoning in patients presenting with a history of drug use with neurological symptoms, and they should conduct follow-up arterial blood gases, electrolytes and ECG as voodoo may contain potentially fatal psychoactive substances.

Indexed as

Poison Control CentersSubstance-Related DisordersAdolescentAdultEgyptFemaleHospitals, UniversityHumansMaleRetrospective StudiesYoung AdultEgyptNew psychoactive substancesToxicityVoodoo

Identifiers

PMID34544462
PMCPMC8454133

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