Evidence map›Paper›PMID 34544272›Full record

ArticlemBio2021

Unipolar Peptidoglycan Synthesis in the

Michelle A Williams, Alena Aliashkevich, Elizaveta Krol, Erkin Kuru, Jacob M Bouchier, Jonathan Rittichier, Yves V Brun, Michael S VanNieuwenhze, Anke Becker, Felipe Cava and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. The polar landscape of bacterial pathogens and predators.Current opinion in microbiology · 2026
    Review
  2. Defining the order of assembly of theJournal of bacteriology · 2026
    Article
  3. Article
  4. Article
  5. Defining the order of assembly of thebioRxiv : the preprint server for biology · 2026
    Article
  6. Peptidoglycan LD-Transpeptidases.Antibiotics (Basel, Switzerland) · 2025
    Review
  7. Twin-arginine transport complex plays an essential role inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Peptidoglycan polymerase function and regulation.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. ISME communications · 2025
    Article
  15. Article
  16. Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Michelle A WilliamsDivision of Biological Sciences, University of Missourigrid.134936.a, Columbia, Missouri, USA.
Alena AliashkevichDepartment of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Centre for Microbial Research, Umeå Universitygrid.12650.30, Umeå, Sweden.
Elizaveta KrolCenter for Synthetic Microbiology (SYNMIKRO), Philipps University Marburg, Marburg, Germany.
Erkin KuruDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Jacob M BouchierDivision of Biological Sciences, University of Missourigrid.134936.a, Columbia, Missouri, USA.
Jonathan RittichierDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Yves V BrunDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Michael S VanNieuwenhzeDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Anke BeckerCenter for Synthetic Microbiology (SYNMIKRO), Philipps University Marburg, Marburg, Germany.
Felipe CavaDepartment of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Centre for Microbial Research, Umeå Universitygrid.12650.30, Umeå, Sweden.ORCID 0000-0001-5995-718X
Pamela J B BrownDivision of Biological Sciences, University of Missourigrid.134936.a, Columbia, Missouri, USA.ORCID 0000-0002-7558-7155
Indiana University Bloomington · USUniversity of Missouri · USPhilipps University of Marburg · DEUmeå University · SEUniversité de Montréal · CA

Funding

Dynamics of bacterial peptidoglycan synthesisR01GM113172 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V, VANNIEUWENHZE, MICHAEL S · 2015 to 2018
$3.5M
Supplement to Chemical Biology Studies of the Dynamics and Inhibition of Peptidoglycan BiosynthesisR35GM136365 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI VANNIEUWENHZE, MICHAEL S · 2020 to 2024
$2.0M
Bacterial Subcellular Organization and its Impact on Growth, Development, Aging, and Surface AdhesionR35GM122556 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V · 2017 to 2019
$1.6M
NIGMS NIH HHS R01 GM113172NIGMS NIH HHS R35 GM122556NIGMS NIH HHS R35 GM136365
6 · The paper itself

Abstract

Members of the

Indexed as

AlphaproteobacteriaBacterial ProteinsCell WallPenicillin-Binding ProteinsPeptidoglycanBacterial ProteinsPenicillin-Binding ProteinsPeptidoglycanAgrobacterium tumefacienscell envelopecell wallpenicillin-binding proteinspeptidoglycanpolar growthRhizobiales

Identifiers

PMID34544272
PMCPMC8546619
OpenAlexW3198993868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.