Evidence map›Paper›PMID 34544269›Full record

ArticleAIDS research and human retroviruses2022

Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use.

Kate M Guthrie, Rochelle K Rosen, Melissa Guillen, Jaime J Ramirez, Sara E Vargas, Joseph L Fava, Anthony S Ham, David F Katz, Susan Cu-Uvin, Sheila Tumilty and 3 more

Open access · greenAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kate M GuthrieCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.ORCID 0000-0002-5528-1212
Rochelle K RosenCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Melissa GuillenCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Jaime J RamirezCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Sara E VargasCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Joseph L FavaCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Anthony S HamImQuest BioSciences, Frederick, Maryland, USA.
David F KatzDepartments of Bioengineering and Obstetrics and Gynecology, Duke University, Durham, North Carolina, USA.
Susan Cu-UvinDepartment of Obstetrics and Gynecology and Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Sheila TumiltyDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Kelley A SmithCenter for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, Rhode Island, USA.
Karen W BuckheitImQuest BioSciences, Frederick, Maryland, USA.
Robert W BuckheitImQuest BioSciences, Frederick, Maryland, USA.
Brown University · USMiriam Hospital · USImQuest BioSciences (United States) · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dual compartment suppositories are being developed to prevent HIV and other sexually transmitted infections. Such products, for use in the rectum, the vagina, or both, could have a significant public health impact by decreasing global incidence of these diseases. In this study, 16 women each used two rheologically distinct suppositories in their vagina and rectum. User Sensory Perception and Experience (USPE) scales assessed sensory experiences during sexual activity to understand whether, and how, women perceive formulation properties in the vagina and rectum. Qualitative data from individual in-depth interviews captured women's descriptions and comparisons of the experiences. Significant differences and large Cohen's

Indexed as

HIV InfectionsRectumAdministration, IntravaginalFemaleHumansSensationSuppositoriesSuppositoriesdual compartment productsperceptibilityrectal HIV preventionsensory experiencessuppositoriesvaginal HIV prevention

Identifiers

PMID34544269
PMCPMC9297320
OpenAlexW3199501287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.