Evidence map›Paper›PMID 34544134›Full record

ArticleG3 (Bethesda, Md.)2021

Efficient construction of a linkage map and haplotypes for Mentha suaveolens using sequence capture.

Helen Tsai, Nestor Kippes, Alana Firl, Meric Lieberman, Luca Comai, Isabelle M Henry

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Layer-specific genetic variation unlocks secondary metabolite diversity in long-lived clonal peppermint.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helen TsaiDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.
Nestor KippesDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.
Alana FirlDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.
Meric LiebermanDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.
Luca ComaiDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.
Isabelle M HenryDepartment of Plant Biology and Genome Center, University of California, Davis, Davis, CA 95616, USA.ORCID 0000-0002-6796-1119

Funding

Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIH HHS S10 OD010786
6 · The paper itself

Abstract

The sustainability of many crops is hindered by the lack of genomic resources and a poor understanding of natural genetic diversity. Particularly, application of modern breeding requires high-density linkage maps that are integrated into a highly contiguous reference genome. Here, we present a rapid method for deriving haplotypes and developing linkage maps, and its application to Mentha suaveolens, one of the diploid progenitors of cultivated mints. Using sequence-capture via DNA hybridization to target single nucleotide polymorphisms (SNPs), we successfully genotyped ∼5000 SNPs within the genome of >400 individuals derived from a self cross. After stringent quality control, and identification of nonredundant SNPs, 1919 informative SNPs were retained for linkage map construction. The resulting linkage map defined a total genetic space of 942.17 cM divided among 12 linkage groups, ranging from 56.32 to 122.61 cM in length. The linkage map is in good agreement with pseudomolecules from our preliminary genome assembly, proving this resource effective for the correction and validation of the reference genome. We discuss the advantages of this method for the rapid creation of linkage maps.

Indexed as

MenthaChromosome MappingGenetic LinkageHaplotypesHumansPlant BreedingPolymorphism, Single NucleotideQuantitative Trait Locilinkage mapmapping-by-sequencingMenthamethodsequence capture

Identifiers

PMID34544134
PMCPMC8496254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.