Evidence map›Paper›PMID 34543647›Full record

Observational studyThe American journal of medicine2022

Nasal Feeding Tubes Are Associated with Fewer Adverse Events than Feeding via Ostomy in Hospitalized Patients Receiving Enteral Nutrition.

Chip Alex Bowman, Elizabeth Hutchins, Marissa Burgermaster, Vivek Sant, David S Seres

Open access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in The American journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Long-term enteral nutrition with a nasogastric tube can be safe and effective: A case report.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Chip Alex BowmanDepartment of Medicine, Mount Sinai Hospital, New York, NY.
Elizabeth HutchinsDepartment of Medicine, Harbor UCLA Medical Center, Torrance, Calif.
Marissa BurgermasterDepartment of Nutritional Sciences, Dell Medical School, University of Texas at Austin, Austin.
Vivek SantDepartment of Surgery, NYU School of Medicine, New York, NY.
David S SeresInstitute of Human Nutrition and Department of Medicine, Columbia Univeristy Irving Medical Center, New York, NY. Electronic address: dss2135@cumc.columbia.edu.
Columbia University Irving Medical Center · USMount Sinai Hospital · USNew York University · USThe University of Texas at Austin · USUCLA Medical Center · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
POSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7M
CARDIOVASCULAR SCIENTIST TRAINING PROGRAMT32HL007895 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM, WATSON, KAROL E · 1998 to 2023
$9.2M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
NCATS NIH HHS UL1 TR001873NHLBI NIH HHS T32 HL007343NHLBI NIH HHS T32 HL007895NICHD NIH HHS P2C HD042849
6 · The paper itself

Abstract

backgroundSurgical feeding ostomies (eg, gastrostomy) have become required by many nursing facilities for all patients receiving enteral nutrition, whether for short- or long-term use. These policies lack supportive evidence. Comparisons of adverse event rates between surgical and natural orifice tubes are few and lacking in the inpatient setting. Additionally, we hypothesize that adverse events related to feeding tubes are underreported. We sought to quantify adverse events to test the relative safety of surgical feeding ostomies and natural orifice (eg. nasogastric or orogastric) feeding tubes in hospitalized patients.

methodsThis was a prospective observational cohort study of enterally fed inpatients using semiweekly focused physical examination, scripted survey, and chart review.

resultsAll tube-fed patients admitted to a large, urban, academic hospital received semiweekly bedside evaluation and chart review over a 9-week period (n = 226 unique patients, mean 6.25 visits each, total 1118 observations). Demographics were comparable between 148 subjects with natural orifice and 113 subjects with surgical feeding tubes. A higher incidence of adverse events was observed with surgical tubes (3.34 vs 1.25 events per 100 subject days, P < .001). Only 50% of all adverse events were documented in the medical record. More patients with surgical tubes were discharged to skilled nursing facilities (58% vs 24%).

conclusionsSurgical feeding tubes are associated with significantly higher in-hospital adverse event rates when compared with natural orifice (nasal or oral) feeding tubes. Policies requiring surgical feeding ostomies should be reevaluated.

Indexed as

AgedEnteral NutritionFemaleGastrostomyHumansInpatientsIntubation, GastrointestinalMaleMiddle AgedNew York CityProspective StudiesEnteral nutritionGastrostomyNasogastric feeding tubeTube feeding complications

Identifiers

PMID34543647
PMCPMC8688227
OpenAlexW3199024231

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.