Evidence map›Paper›PMID 34543125›Full record

ArticleInfection and immunity2021

Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen.

Nina J Gao, Ervin Rodas Lima, Victor Nizet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Serological Responses toOpen forum infectious diseases · 2024
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nina J GaoBiomedical Sciences Graduate Program, UC San Diego, La Jolla, California, USA.
Ervin Rodas LimaDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA.
Victor NizetBiomedical Sciences Graduate Program, UC San Diego, La Jolla, California, USA.ORCID 0000-0003-3847-0422

Funding

Training Program in Basic Clinical GeneticsT32GM008666 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMILTON, BRUCE A · 1998 to 2021
$8.6M
GAS Switch from Colonizing Bacterium to Invasive PathogenR01AI077780 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 2008 to 2019
$3.8M
NIAID NIH HHS R01 AI077780NIGMS NIH HHS T32 GM008666
6 · The paper itself

Abstract

Group A Streptococcus (GAS) is a preeminent human bacterial pathogen causing hundreds of millions of infections each year worldwide. In the clinical setting, the bacterium is easily identified by a rapid antigen test against the group A carbohydrate (GAC), a polysaccharide that comprises 30 to 50% of the GAS cell wall by weight. Originally described by Rebecca Lancefield in the 1930s, GAC consists of a polyrhamnose backbone and a

Indexed as

Antigens, BacterialDisease SusceptibilityHost-Pathogen InteractionsHumansImmunityPolysaccharides, BacterialStreptococcal InfectionsStreptococcus pyogenesVirulenceVirulence FactorsAntigens, BacterialPolysaccharides, Bacterialstreptococcal polysaccharide group AVirulence Factorsautoimmunitycell wallGlcNAcgroup A carbohydrategroup A StreptococcusLancefield antigenrheumatic heart diseaseStreptococcus pyogenesvaccinevirulence factor

Identifiers

PMID34543125
PMCPMC8594609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.