Evidence map›Paper›PMID 34543107›Full record

ArticleJournal of bacteriology2021

An AraC/XylS Family Transcriptional Regulator Modulates the Oxidative Stress Response of Francisella tularensis.

Dina Marghani, Zhuo Ma, Anthony J Centone, Weihua Huang, Meenakshi Malik, Chandra Shekhar Bakshi

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dina Marghani *Department of Pathology, Microbiology, and Immunology, New York Medical Collegegrid.260917.b, Valhalla, New York, USA.
Zhuo Ma *Department of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciencesgrid.413555.3, Albany, New York, USA.
Anthony J CentoneDepartment of Pathology, Microbiology, and Immunology, New York Medical Collegegrid.260917.b, Valhalla, New York, USA.
Weihua HuangDepartment of Pathology, Microbiology, and Immunology, New York Medical Collegegrid.260917.b, Valhalla, New York, USA.
Meenakshi MalikDepartment of Basic and Clinical Sciences, Albany College of Pharmacy and Health Sciencesgrid.413555.3, Albany, New York, USA.
Chandra Shekhar BakshiDepartment of Pathology, Microbiology, and Immunology, New York Medical Collegegrid.260917.b, Valhalla, New York, USA.ORCID 0000-0001-5459-3225
New York Medical College · USAlbany College of Pharmacy and Health Sciences · US

Funding

Repression of Inflammasome by Francisella tularensisR15AI107698 · NIAID · ALBANY COLLEGE OF PHARMACY · PI MALIK, MEENAKSHI · 2013 to 2024
$1.9M
Advancement of a Mucosal Subunit Vaccine in an Outbred Model of Respiratory TularemiaR21AI151277 · NIAID · NEW YORK MEDICAL COLLEGE · PI BAKSHI, CHANDRA SHEKHAR, REED, DOUGLAS SCOTT · 2020 to 2021
$446k
Modulation of host innate immune response by Francisella tularensisR56AI101109 · NIAID · NEW YORK MEDICAL COLLEGE · PI BAKSHI, CHANDRA SHEKHAR · 2013 to 2013
$390k
NIAID NIH HHS R15 AI107698NIAID NIH HHS R21 AI151277NIH HHS R15AI107698NIH HHS R56AI101109
6 · The paper itself

Abstract

Francisella tularensis is a Gram-negative bacterium that causes a fatal human disease known as tularemia. The Centers for Disease Control and Prevention have classified F. tularensis as a category A tier 1 select agent. The virulence mechanisms of

Indexed as

AnimalsAraC Transcription FactorDown-RegulationFrancisella tularensisGene DeletionGene Expression Regulation, BacterialGenetic Complementation TestMiceMice, Inbred C57BLOxidative StressTularemiaVirulenceAraC Transcription FactorAraC/XylSFrancisella tularensisoxidative stresspathogenesistranscriptional regulationvirulence

Identifiers

PMID34543107
PMCPMC8570275
OpenAlexW3199548429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.