Evidence map›Paper›PMID 34543091›Full record

ArticleAntimicrobial agents and chemotherapy2021

Antifungal Susceptibility of 182 Fusarium Species Isolates from 20 European Centers: Comparison between EUCAST and Gradient Concentration Strip Methods.

Marion Blaize, Anne-Cecile Normand, Sebastien Imbert, Abdullah M S Al-Hatmi, Erja Chryssanthou, Sophie Cassaing, Christine Schuttler, Lilia Hasseine, Caroline Mahinc, Damien Costa and 13 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Clinical Features and Outcomes of InvasiveJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. High azole MICs in Fusarium spp.: a key factor in treatment decisions for cancer patients?Revista do Instituto de Medicina Tropical de Sao Paulo · 2025
    Article
  5. In Vitro Sensitivity Test ofPathogens (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Clinical utility of antifungal susceptibility testing.JAC-antimicrobial resistance · 2022
    Review
  13. Article
  14. Disseminated AngioinvasiveCase reports in oncology
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 20 institutions in 8 countries.

Marion BlaizeAP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
Anne-Cecile NormandAP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.ORCID 0000-0002-9589-4603
Sebastien ImbertAP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
Abdullah M S Al-HatmiCentre of Expertise in Mycology, Radboud University Medical Centre, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID 0000-0002-5206-2647
Erja ChryssanthouDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Sophie CassaingCHU Toulouse, Service de Parasitologie-Mycologie, Toulouse, France.
Christine SchuttlerLaboratoire Biogroup-LCD, Levallois, France.
Lilia HasseineCHU de Nice, Service de Parasitologie Mycologie, Nice, France.
Caroline MahincCHU de Saint-Etienne, Service de Parasitologie Mycologie, Saint-Etienne, France.
Damien CostaCentre Hospitalier Universitaire de Rouen, Service de Parasitologie Mycologie, Rouen, France.
Christine BonnalAP-HP, Hôpital Bichat-Claude Bernard, Service de Parasitologie Mycologie, Paris, France.
Stéphane RanqueAix Marseille University, IRD, AP-HM, SSA, VITROME, IHU Méditerranée Infection, Marseille, France.ORCID 0000-0003-3293-5276
Marc SautourCHU de Dijon, Service de Parasitologie Mycologie, Dijon, France.
Elisa RubioDepartment of Microbiology, ISGlobal Barcelona Institute for Global Health, Barcelona, Spain.
Laurence DelhaesCHU de Bordeaux, Groupe Hospitalier Pellegrin, Service de Mycologie, Bordeaux, France.
Arnaud RiatGeneva University Hospitals, Bacteriology Laboratory, Geneva, Switzerland.
Boualem SendidCHU de Lille, Department Parasitology-Mycology, Lille, France.
Lise KristensenAarhus University Hospital, Department of Clinical Microbiology, Aarhus, Denmark.
Marcel BrandenbergerLabor Synlab Luzern, Lucerne, Switzerland.
Dirk StubbeSciensano, BCCM/IHEM Collection, Mycology and Aerobiology Unit, Brussels, Belgium.
Sophie BrunAP-HP, Hôpital Avicenne, Service de Parasitologie-Mycologie, Bobigny, France.
Renaud PiarrouxAP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.
Arnaud FekkarAP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie Mycologie, Paris, France.ORCID 0000-0001-9954-075X
Centre National de la Recherche Scientifique · FRSorbonne Université · FRAarhus University Hospital · DKAix-Marseille Université · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Lille · FRCentre Hospitalier Universitaire de Nice · FRCentre Hospitalier Universitaire de Rouen · FRCentre Hospitalier Universitaire de Saint-Étienne · FRCentre Hospitalier Universitaire de Toulouse · FRCHU Dijon Bourgogne · FRHospital Clínic de Barcelona · ESInserm · FRKarolinska Institutet · SERadboud University Nijmegen · NLSciensano (Belgium) · BEUniversité Claude Bernard Lyon 1 · FRUniversity Hospital of Geneva · CHUniversity of Teacher Education Lucerne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We determined the susceptibility of 182 Fusarium species isolates to five antifungal drugs (amphotericin B, voriconazole, posaconazole, isavuconazole, and terbinafine) by the EUCAST method. Based on the latest taxonomic insights, isolates collected from 20 European centers were distributed into seven complexes and 27 species. The susceptibility was variable, depending on the species. Comparison with the gradient concentration strip method, which was used for 77 isolates, showed essential agreement values for voriconazole, posaconazole, isavuconazole, and amphotericin B of 17%, 91%, 83%, and 70%, respectively.

Indexed as

Antifungal AgentsFusariumAmphotericin BMicrobial Sensitivity TestsVoriconazoleAmphotericin BAntifungal AgentsVoriconazoleamphotericin Bantifungal susceptibilitycomparisonEtestEUCASTFusariumgradient concentration stripsisavuconazoleposaconazoleterbinafinevoriconazole

Identifiers

PMID34543091
PMCPMC8597759
OpenAlexW3201529471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.