Evidence map›Paper›PMID 34542823›Full record

ArticleApplied biochemistry and biotechnology2021

Synthesis of β-Glucan Nanoparticles from Red Algae-Derived β-Glucan for Potential Biomedical Applications.

Ramalingam Parthasarathy, Seetharaman Prabu Kumar, H C Yashavantha Rao, Jayabaskaran Chelliah

Abstract read
PubMed Publisher
In one paragraph

Article in Applied biochemistry and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. β-glucan nanoparticles alleviate acute asthma by suppressing ferroptosis and DNA damage in mice.Apoptosis : an international journal on programmed cell death · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ramalingam ParthasarathyDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India. sarathy20bioinfo@gmail.com.
Seetharaman Prabu KumarLaboratory of Functional Molecules and Materials, School of Physics and Optoelectronic Engineering, Shandong University of Technology, 255000, Xincun West Road 266, Zibo, China.
H C Yashavantha RaoDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Jayabaskaran ChelliahDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Indian Institute of Science Bangalore · INShandong University of Technology · CN

Funding

DST-SERB,India PDF/2017/001184ugc, kothari fellowship F.4_2/2006 (BSR)/BL/17-18/0234
6 · The paper itself

Abstract

The present study highlights/demonstrates facile synthesis of β-Glucan nanoparticles (β-GluNPs) that can be used in the prevention of breast cancer and other infectious diseases. Moreover, this method is inexpensive and shows effectivity towards different biological applications. Further, the characterization of synthesized β-GluNPs was exclusively confirmed through UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), zeta potential, scanning electron microscopy (SEM), high resolution-transmission electron microscopy (HR-TEM), and X-ray powder diffraction (XRD) analysis. The synthesized β-GluNPs were further confirmed by FT-IR spectroscopy. The HR-TEM results demonstrated that the formation of polydispersed nanoparticles with a mean size of 20 ± 5 nm. The hydrostatic zeta potential was - 22.7 mV, which indicated their colloidal stability. The XRD pattern revealed the crystalline nature of the nanoparticles. Besides, β-GluNPs showed better antibacterial activity against the tested pathogens. The apoptosis and DNA fragmentation observed to be IC

Indexed as

Anti-Bacterial AgentsAntineoplastic Agentsbeta-GlucansNanoparticlesHumansMCF-7 CellsRhodophytaAnti-Bacterial AgentsAntineoplastic Agentsbeta-GlucansAntibacterial activityAnticancer activityDNA fragmentation assayDual stainingGracilaria corticata (Gco)β-Glucan nanoparticles

Identifiers

PMID34542823
OpenAlexW3154836135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.