Evidence map›Paper›PMID 34542779›Full record

ArticleAIDS and behavior2022

Change in Alcohol Use Based on Self-Report and a Quantitative Biomarker, Phosphatidylethanol, in People With HIV.

Kathleen A McGinnis, Janet P Tate, Kendall J Bryant, Amy C Justice, Patrick G O'Connor, Maria C Rodriguez-Barradas, Stephen Crystal, Christopher J Cutter, Nathan B Hansen, Stephen A Maisto and 8 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01410123 (Integrated Stepped Care for Unhealthy Alcohol Use in HIV), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01410123 nacompletednot on this map

Integrated Stepped Care for Unhealthy Alcohol Use in HIV

TypeinterventionalSponsorYale UniversityRan2013 to 2018Enrolled319ConditionsLiver Diseases, Alcoholic, Alcoholism, HIV, Hepatitis CArmsIntegrated Stepped Care (ISC), Treatment as Usual
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kathleen A McGinnisVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA. kathleen.mcginnis3@va.gov.ORCID http://orcid.org/0000-0003-4844-3372
Janet P TateVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA.
Kendall J BryantNational Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
Amy C JusticeVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA.
Patrick G O'ConnorYale School of Medicine, New Haven, CT, USA.
Maria C Rodriguez-BarradasInfectious Diseases Section, Michael E. DeBakey VAMC and Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Stephen CrystalInstitute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA.
Christopher J CutterYale School of Medicine, New Haven, CT, USA.
Nathan B HansenCollege of Public Health, University of Georgia, Athens, GA, USA.
Stephen A MaistoDepartment of Psychology, Syracuse University, Syracuse, NY, USA.
Vincent C MarconiSchool of Medicine and Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Emily C WilliamsDepartment of Health Systems and Population Health, University of Washington School of Public Health and Seattle-Denver Health Services Research & Development Center of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound Healthcare System, Seattle, WA, USA.
Robert L CookDepartment of Epidemiology, University of Florida, Gainesville, FL, USA.
Adam J GordonUniversity of Utah and Salt Lake City VA Health Care System, Salt Lake City, UT, USA.
Kirsha S GordonVA Connecticut Healthcare System, US Department of Veterans Affairs, West Haven, CT, USA.
Oghenowede EyawoSchool of Global Health, York University, Toronto, ON, Canada.
E Jennifer EdelmanYale School of Medicine, New Haven, CT, USA.
David A FiellinYale School of Medicine, New Haven, CT, USA.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Integrated Stepped Care for Unhealthy Alcohol Use in HIVU01AA020795 · NIAAA · YALE UNIVERSITY · PI FIELLIN, DAVID · 2011 to 2020
$5.2M
National Institute of Allergy and Infectious Diseases P30AI050409NIAAA NIH HHS U01-AA020790NIAAA NIH HHS U01-AA020795NIAAA NIH HHS U10-AA13566NIAAA NIH HHS U24-AA020794
6 · The paper itself

Abstract

The timeline followback (TLFB) takes more resources to collect than the Alcohol Use Disorder Identification Test (AUDIT-C). We assessed agreement of TLFB and AUDIT-C with the biomarker phosphatidylethanol (PEth) and compared changes in TLFB and PEth among persons with HIV (PWH) using secondary data from randomized trials. We calculated operating characteristics and agreement between TLFB (> 1 and > 2 average drinks/day), AUDIT-C ≥ 4 and PEth ≥ 20 among 275 men with HIV. Median age was 57 years, 80% were African-American; and 17% white. Sixty-eight percent had PEth ≥ 20, 46% reported > 2 average drinks/day on TLFB, 61% reported > 1 average drinks/day on TLFB, and 72% had an AUDIT-C ≥ 4. Relative to PEth, sensitivity for AUDIT-C ≥ 4 was 84% (kappa = 0.36), and for TLFB > 1 average drink/day was 76% (kappa = 0.44). Change in alcohol use appeared greater using TLFB measures than PEth. Strategies to robustly assess alcohol use in PWH may require both self-report and biomarkers.

Indexed as

HIV InfectionsAlcohol DrinkingBiomarkersGlycerophospholipidsHumansMaleMiddle AgedSelf ReportBiomarkersGlycerophospholipidsphosphatidylethanolAlcohol consumptionHIV infectionPhosphatidylethanolamine

Identifiers

PMID34542779

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.