Evidence map›Paper›PMID 34542696›Full record

ArticleEuropean radiology2022

Diagnostic performance of MR black-blood thrombus imaging for cerebral venous thrombosis in real-world clinical practice.

Xiaoxu Yang, Fang Wu, Yuehong Liu, Jiangang Duan, Marc Fisher, Xunming Ji, Ran Meng, Huibo Zhang, Zhaoyang Fan, Qi Yang

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Study on Cerebral Venous Thrombosis From 2014 to 2023: A Bibliometric Analysis via CiteSpace.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
  12. Explore the Staging of Cerebral Venous Thrombosis Through Fibrinolytic Indicators.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Xiaoxu YangDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti Nanlu, Chaoyang District, Beijing, 100020, China.
Fang WuDepartment of Radiology, Xuanwu Hospital, Beijing, China.
Yuehong LiuDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti Nanlu, Chaoyang District, Beijing, 100020, China.
Jiangang DuanDepartment of Emergency, Xuanwu Hospital, Beijing, China.
Marc FisherNeurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Beijing, China.
Ran MengDepartment of Neurology, Xuanwu Hospital, Beijing, China.
Huibo ZhangDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti Nanlu, Chaoyang District, Beijing, 100020, China.
Zhaoyang FanRadiology and Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA. zhaoyang.fan@med.usc.edu.
Qi YangDepartment of Radiology, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti Nanlu, Chaoyang District, Beijing, 100020, China. yangyangqiqi@gmail.com.ORCID http://orcid.org/0000-0002-5773-0456
Beijing Xuanwu Traditional Chinese Medicine Hospital · CNCapital Medical University · CNBeijing Chao-Yang Hospital, Capital Medical University · CNBeth Israel Deaconess Medical Center · USUniversity of Southern California · US

Funding

Longitudinal and quantitative MR plaque imaging for prediction of response to medical management in symptomatic intracranial atherosclerosisR01HL147355 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG · 2019 to 2023
$2.1M
NIH HHS R01 HL147355
6 · The paper itself

Abstract

objectivesMR black-blood thrombus imaging (BTI) has been developed for the detection of cerebral venous thrombosis (CVT). Yet, there is a lack of real-world data to verifying its clinical performance. This study aims to evaluate the performance of BTI in diagnosing and staging CVT in a 5-year period.

methodsPatients suspected of CVT were enrolled between 2014 and 2019. Patients with or without BTI scans were classified into group A and group B, respectively. The prevalence of correct diagnosis of CVT and patients with evaluable clot age were compared. The diagnostic performance of BTI including sensitivity, specificity, and specific staging information was further analyzed.

resultsTwo hundred and twenty-one of the 308 patients suspected of CVT were eligible in the current study (114 in group A and 97 in group B), with 125 diagnosed by multidisciplinary teams to have CVTs (56 in group A, 69 in group B). The rate of correct diagnosis of CVT was higher in group A than that in group B (94.7% vs 60.8%, p < 0.001, x

conclusionsIn the actual clinical practice, BTI improves diagnostic confidence and has an excellent performance in confirming and staging CVT. KEY POINTS: • Black-blood thrombus imaging has good diagnostic performance in detecting cerebral venous thrombosis compared to traditional imaging methods with strong evidence in the actual clinical setting. • BTI helps clinicians to diagnose CVT with more accuracy and confidence, which can be served as a promising imaging examination. • BTI can also provide additional information of different thrombus ages objectively, the valuable reference for clinical strategy.

Indexed as

Intracranial ThrombosisThrombosisVenous ThrombosisHumansMagnetic Resonance ImagingDiagnosis imagingMagnetic resonance imagingSensitivity and specificityVenous thrombosis

Identifiers

PMID34542696
OpenAlexW3200617435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.