ArticleAngewandte Chemie (International ed. in English)2021
Tuneable Time Delay in the Burst Release from Oxidation-Sensitive Polymersomes Made by PISA.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- pH-Responsive polymeric vesicles preparedRSC advances · 2025Article
- Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post-Assembly Loading.Advanced biology · 2025Article
- Kinetically Controlled and Nonequilibrium Assembly of Block Copolymers in Solution.Journal of the American Chemical Society · 2024Review
- Polymeric Nanoparticles for Drug Delivery.Chemical reviews · 2024Review
- Artificial cell synthesis using biocatalytic polymerization-induced self-assembly.Nature chemistry · 2024Article
- One-pot asymmetric living copolymerization-induced chiral self-assemblies and circularly polarized luminescence.Chemical science · 2024Article
- Dissipative Particle Dynamic Simulation on Self-Assembly of Symmetric CBABC Pentablock Terpolymers in Solution.Materials (Basel, Switzerland) · 2023Article
- Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly.Polymers · 2023Article
- Thioanisole ester based logic gate cascade to control ROS-triggered micellar degradation.Polymer chemistry · 2022Article
- RAFT-mediated polymerization-induced self-assembly (RAFT-PISA): current status and future directions.Chemical science · 2022Review
- Tuneable Time Delay in the Burst Release from Oxidation-Sensitive Polymersomes Made by PISA.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Reactive polymersomes represent a versatile artificial cargo carrier system that can facilitate an immediate release in response to a specific stimulus. The herein presented oxidation-sensitive polymersomes feature a time-delayed release mechanism in an oxidative environment, which can be precisely adjusted by either tuning the membrane thickness or partial pre-oxidation. These polymeric vesicles are conveniently prepared by PISA allowing the straightforward and effective in situ encapsulation of cargo molecules, as shown for dyes and enzymes. Kinetic studies revealed a critical degree of oxidation causing the destabilization of the membrane, while no release of the cargo is observed beforehand. The encapsulation of glucose oxidase directly transforms these polymersomes into glucose-sensitive vesicles, as small molecules including sugars can passively penetrate their membrane. Considering the ease of preparation, these polymersomes represent a versatile platform for the confinement and burst release of cargo molecules after a precisely adjustable time span in the presence of specific triggers, such as H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.