Trial reportThe Laryngoscope2022
Benefits of Cochlear Implantation in Childhood Unilateral Hearing Loss (CUHL Trial).
Trial report in The Laryngoscope, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05775367 (Cochlear Implantation in Infants and Toddlers With Single-Sided Deafness), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cochlear Implantation in Infants and Toddlers With Single-Sided Deafness
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hearing implants in pediatrics with cochlear nerve deficiency: an updated systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Pooled it
- Rehabilitation Strategies for Pediatric Single-Sided Deafness, Including Children with Asymmetric Hearing Loss: A Systematic Review.Audiology research · 2026Review
- Longitudinal Cochlear Implant Use in Pediatric Patients With Unilateral Hearing Loss.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Executive Functioning in Single-Sided Deafness: A Pediatric Comparison with Temporal Lobe Epilepsy.Journal of clinical medicine · 2026Article
- Determinants of Cochlear Implant Evaluation Completion and Uptake in Children.Journal of clinical medicine · 2026Article
- Personalizing Cochlear Implant Care in Single-Sided Deafness: A Distinct Paradigm from Bilateral Hearing Loss.Journal of personalized medicine · 2025Review
- The Relationship Between Daily Device Use and Subjective Hearing Abilities in Pediatric Cochlear Implant Users.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Cochlear implantation for children with single-sided deafness: parents' perspectives.Journal of the Royal Society of New Zealand · 2025Article
- [Assessment of auditory perception of children with single-sided deafness after cochlear implantation].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Article
- Unilateral Sensorineural Hearing Loss in Children: Etiology, Audiological Characteristics, and Treatment.Children (Basel, Switzerland) · 2024Article
- Cochlear Implantation in Children Affected by Single-Sided Deafness: A Comprehensive Review.Audiology research · 2024Review
- Congenital Cytomegalovirus and Hearing Loss: The State of the Art.Journal of clinical medicine · 2023Review
- Health-Related Quality of Life in Children With Unilateral Sensorineural Hearing Loss Following Cochlear Implantation.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023Article
- Observational Study of Pediatric Cochlear Implant Recipients: Two-year Follow-up Outcomes.Medeniyet medical journal · 2023Article
- Multiple congenital anomalies and adverse developmental outcomes are associated with neonatal intensive care admission and unilateral hearing loss.Frontiers in pediatrics · 2022Article
- Article
- Long-Term Outcomes of Pediatric Cochlear Implantation for Single-Sided Deafness: A Western Australian Perspective.Ear and hearingArticle
- Article
- Article
- Targeted Auditory Rehabilitation Employing Direct Audio Input in Children With Single-Sided Deafness Using a Cochlear Implant.Ear and hearingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectives/hypothesesChildren with unilateral sensory hearing loss (UHL) struggle to understand speech in noise and locate the origin of sound and have reduced quality of hearing. This clinical trial will determine the benefits of cochlear implantation in children with UHL. STUDY
designProspective clinical trial.
methodsTwenty children with at least moderate to profound sensory hearing loss and poor speech perception (word score <30%) in one ear and normal hearing in the contralateral ear participated in a Food and Drug Administration-approved clinical trial. Subjects were evaluated for speech perception in quiet, speech perception in noise, sound localization, and subjective benefits after implantation.
resultsCNC word score perception in quiet significantly improved (1% to 50%, P < .0001) by 12 months after activation. Speech perception in noise by BKB-SIN significantly improved in all three noise configurations; there was a 3.6 dB advantage in head shadow (P < .0001), a 1.6 dB advantage in summation (P = .003), and a 2.5 dB advantage in squelch (P = .0001). Localization improved by 26° at 9 months (P < .0001). Speech, Spatial, and Qualities (SSQ) demonstrated significant improvements in speech (5.2 to 7.4, P = .0012), qualities of hearing (5.9 to 7.5, P = .0056), and spatial hearing (2.7 to 6.6, P < .0001). SSQ subscales associated with binaural hearing were significantly improved, as was listening effort (P = .0082). Subjects demonstrated a non-significant improvement in fatigue.
conclusionsThis study demonstrates that children with UHL significantly benefit from cochlear implantation. LEVEL OF EVIDENCE: Level 3 Laryngoscope, 132:S1-S18, 2022.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.