Evidence map›Paper›PMID 34541896›Full record

ArticleBrain connectivity2022

Stress-Induced Changes in Effective Connectivity During Regulation of the Emotional Response to Threat.

Adam M Goodman, Muriah D Wheelock, Nathaniel G Harnett, Elizabeth S Davis, Sylvie Mrug, Gopikrishna Deshpande, David C Knight

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain connectivity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05854160 (Stimulation-Induced Changes in Fronto-Limbic Connectivity Control Regulation of the Emotional Response to Threat), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05854160 narecruitingnot on this mapstarted 2023, after this paper: background citation

Stimulation-Induced Changes in Fronto-Limbic Connectivity Control Regulation of the Emotional Response to Threat

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2023 to 2027Enrolled30ConditionsEpilepsy, Mental DisordersArmsElectrical Pulse Train Stimulation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Potentiation of the MNeurobiology of disease · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam M GoodmanDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Muriah D WheelockDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Nathaniel G HarnettDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Elizabeth S DavisDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Sylvie MrugDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Gopikrishna DeshpandeAuburn University MRI Research Center, Department of Electrical and Computer Engineering, Auburn University, Auburn, Alabama, USA.
David C KnightDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-1094-801X

Funding

Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
Neurobiological Mechanisms of Lower Internalizing Disorders in Black AmericansR01MH098348 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KNIGHT, DAVID C, MRUG, SYLVIE · 2012 to 2016
$2.9M
NIA NIH HHS P30 AG066444NIMH NIH HHS R01 MH098348
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainEmotionsAmygdalaConditioning, ClassicalFearHumansMagnetic Resonance ImagingPrefrontal Cortexeffective connectivityfMRIneural networkPavlovian Conditioned Diminutionpsychosocial stressstress disruption

Identifiers

PMID34541896
PMCPMC9634990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.