Evidence map›Paper›PMID 34541584›Full record

ArticleArtificial intelligence in medicine. Conference on Artificial Intelligence in Medicine (2005- )2021

Identifying Symptom Clusters Through Association Rule Mining.

Mikayla Biggs, Carla Floricel, Lisanne Van Dijk, Abdallah S R Mohamed, C David Fuller, G Elisabeta Marai, Xinhua Zhang, Guadalupe Canahuate

Abstract read
In one paragraph

Article in Artificial intelligence in medicine. Conference on Artificial Intelligence in Medicine (2005- ), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Improving Survival Prediction of Head and Neck Cancer Patients by Modeling Long-term Symptom Burden.Proceedings. IEEE International Conference on Healthcare Informatics · 2026
    Article
  2. L-VISP: LSTM Visualization for Interpretable Symptom Prediction in Patient Cohorts.Computer graphics forum : journal of the European Association for Computer Graphics · 2026
    Article
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  7. THALIS: Human-Machine Analysis of Longitudinal Symptoms in Cancer Therapy.IEEE transactions on visualization and computer graphics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mikayla BiggsUniversity of Iowa, Iowa City, IA, USA.
Carla FloricelUniversity of Illinois in Chicago, Chicago, IL, USA.
Lisanne Van DijkUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Abdallah S R MohamedUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
C David FullerUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
G Elisabeta MaraiUniversity of Illinois in Chicago, Chicago, IL, USA.
Xinhua ZhangUniversity of Illinois in Chicago, Chicago, IL, USA.
Guadalupe CanahuateUniversity of Iowa, Iowa City, IA, USA.

Funding

Longitudinal Spatial-Nonspatial Decision Support for Competing Outcomes in Head and Neck Cancer TherapyR01CA258827 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2021 to 2025
$2.9M
SMART-ACT: Spatial Methodologic Approaches for Risk Assessment and Therapeutic Adaptation in Cancer TreatmentR01CA214825 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$1.1M
QuBBD: Precision E –Radiomics for Dynamic Big Head & Neck Cancer Data R01CA225190 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$776k
NCI NIH HHS R01 CA214825NCI NIH HHS R01 CA225190NCI NIH HHS R01 CA258827
6 · The paper itself

Abstract

Cancer patients experience many symptoms throughout their cancer treatment and sometimes suffer from lasting effects post-treatment. Patient-Reported Outcome (PRO) surveys provide a means for monitoring the patient's symptoms during and after treatment. Symptom cluster (SC) research seeks to understand these symptoms and their relationships to define new treatment and disease management methods to improve patient's quality of life. This paper introduces association rule mining (ARM) as a novel alternative for identifying symptom clusters. We compare the results to prior research and find that while some of the SCs are similar, ARM uncovers more nuanced relationships between symptoms such as anchor symptoms that serve as connections between interference and cancer-specific symptoms.

Indexed as

Association rule miningPROSymptom clusters

Identifiers

PMID34541584
PMCPMC8444285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.