Evidence map›Paper›PMID 34541582›Full record

ArticleACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine2021

Assigning ICD-O-3 Codes to Pathology Reports using Neural Multi-Task Training with Hierarchical Regularization.

Anthony Rios, Eric B Durbin, Isaac Hands, Ramakanth Kavuluru

Abstract read
In one paragraph

Article in ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. AI assistance in tumor multidisciplinary teams.ESMO real world data and digital oncology · 2026
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anthony RiosDept. of Information Systems & Cyber Security, Cyber Center for Security & Analytics, University of Texas at San Antonio, San Antonio, Texas, USA.
Eric B DurbinDivision of Biomedical Informatics (Internal Medicine), Kentucky Cancer Registry, University of Kentucky, Lexington, Kentucky, USA.
Isaac HandsKentucky Cancer Registry, Lexington, Kentucky, USA.
Ramakanth KavuluruDivision of Biomedical Informatics (Internal Medicine), University of Kentucky, Lexington, Kentucky, USA.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
Advanced End-to-End Relation Extraction with Deep Neural NetworksR01LM013240 · NLM · UNIVERSITY OF KENTUCKY · PI KAVULURU, VENKATA NAGA RAMAKANTH · 2020 to 2023
$1.4M
NCI NIH HHS P30 CA177558NLM NIH HHS R01 LM013240
6 · The paper itself

Abstract

Tracking population-level cancer information is essential for researchers, clinicians, policymakers, and the public. Unfortunately, much of the information is stored as unstructured data in pathology reports. Thus, too process the information, we require either automated extraction techniques or manual curation. Moreover, many of the cancer-related concepts appear infrequently in real-world training datasets. Automated extraction is difficult because of the limited data. This study introduces a novel technique that incorporates structured expert knowledge to improve histology and topography code classification models. Using pathology reports collected from the Kentucky Cancer Registry, we introduce a novel multi-task training approach with hierarchical regularization that incorporates structured information about the International Classification of Diseases for Oncology, 3rd Edition classes to improve predictive performance. Overall, we find that our method improves both micro and macro F1. For macro F1, we achieve up to a 6% absolute improvement for topography codes and up to 4% absolute improvement for histology codes.

Indexed as

biomedical informaticsnatural language processingneural networks

Identifiers

PMID34541582
PMCPMC8445227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.