Evidence map›Paper›PMID 34541579›Full record

ArticleJournal of cellular signaling2021

NH

Chad M Warren, Monika Halas, Han-Zhong Feng, Beata M Wolska, Jian-Ping Jin, R John Solaro

Open access · hybridAbstract read
In one paragraph

Article in Journal of cellular signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chad M WarrenDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
Monika HalasDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
Han-Zhong FengDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
Beata M WolskaDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
Jian-Ping JinDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
R John SolaroDepartment of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, USA.
University of Illinois Chicago · US

Funding

Sarcomeric Modifications and Progressive Cardiac MaladaptationP01HL062426 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SOLARO, R JOHN · 2000 to 2020
$42.4M
Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
Myofilament signaling and cardiac disordersR01HL128468 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SOLARO, R JOHN, WOLSKA, BEATA M. · 2016 to 2019
$1.6M
NHLBI NIH HHS P01 HL062426NHLBI NIH HHS R01 HL127691NHLBI NIH HHS R01 HL128468
6 · The paper itself

Abstract

Cardiac sarcomeres express a variant of troponin I (cTnI) that contains a unique N-terminal extension of ~30 amino acids with regulatory phosphorylation sites. The extension is important in the control of myofilament response to Ca

Indexed as

Ca2+-sensitivityHeart failureHypertrophic cardiomyopathySarcomeresTropomyosin

Identifiers

PMID34541579
PMCPMC8444995
OpenAlexW3193876746

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.