Evidence map›Paper›PMID 34541575›Full record

ArticleJournal of cellular immunology2021

The Importance of miRNA Identification During Respiratory Viral Infections.

Ivan Martinez-Espinoza, Ma Del Rocio Banos-Lara, Antonieta Guerrero-Plata

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  10. miRNA in Molecular Diagnostics.Bioengineering (Basel, Switzerland) · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ivan Martinez-EspinozaDepartment of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA, USA.
Ma Del Rocio Banos-LaraUniversidad Popular Autonoma del Estado de Puebla, Mexico.
Antonieta Guerrero-PlataDepartment of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA, USA.
Louisiana State University · USUniversidad Popular Autónoma del Estado de Puebla · MX

Funding

The role of adipocyte-driven inflammation and leptin pathway in pulmonary viral infections caused by SARS-CoV-2 and influenza A virusesP20GM130555 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Stephania A Cormier, TAMMY R DUGAS · 2019 to 2026
$19.9M
Role of plasmacytoid dendritic cells in human metapneumo virus infectionR03AI081171 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI GUERRERO-PLATA, MARIA ANTONIETA · 2010 to 2011
$147k
NIAID NIH HHS R03 AI081171NIGMS NIH HHS P20 GM130555
6 · The paper itself

Abstract

The expression of small non-coding RNA MicroRNAs (miRNAs) during respiratory viral infections is of critical importance as they are implicated in the viral replication, immune responses and severity of disease pathogenesis. Respiratory viral infections have an extensive impact on human health across the globe. For that is essential to understand the factors that regulate the host response against infections. The differential miRNA pattern induced by respiratory viruses has been reported, including include influenza A virus (IAV), human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), adenovirus (AdV), and more recently, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. In this commentary, we highlight the importance of miRNAs identification and the contribution of these molecules in the modulation of the immune response through the upregulation and downregulation of miRNAs expression in different immune and non-immune cells.

Indexed as

HMPVHRSVmiRNAsNon-coding RNAsRespiratory tractRespiratory virusesRSV

Identifiers

PMID34541575
PMCPMC8445226
OpenAlexW3186920013

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.