ReviewHematology, transfusion and cell therapy
ABO blood group association and COVID-19. COVID-19 susceptibility and severity: a review.
Review in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Association of ABO/Rh Blood Groups and ABO Gene VariantsViruses · 2026Article
- Do certain blood groups increase COVID-19 severity and mortality?Global epidemiology · 2025Article
- Trends in Serum Shifts: Unveiling Hyperglycaemia Links Post-COVID-19 Vaccination.Current medicinal chemistry · 2025Article
- Susceptibility and severity of Covid-19 in different blood groups.Bioinformation · 2025Article
- Changes in Pharmacological Approach to COVID-19 in a Referral Hospital in Tehran During Two Years.Tanaffos · 2024Article
- Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease.Virology journal · 2024Article
- Assessment of the COVID-19 pandemic progression in Ecuador through seroprevalence analysis of anti-SARS-CoV-2 IgG/IgM antibodies in blood donors.Frontiers in cellular and infection microbiology · 2024Article
- Epigenetic perspectives associated with COVID-19 infection and related cytokine storm: an updated review.Infection · 2023Review
- COVID-19 in a Portuguese whole blood donor population.Heliyon · 2023Article
- Association between ABO blood group/genotype and COVID-19 in a Japanese population.Annals of hematology · 2023Article
- Role of Trust, Risk Perception, and Perceived Benefit in COVID-19 Vaccination Intention of the Public.Healthcare (Basel, Switzerland) · 2023Article
- Homozygous-Recessive Characteristics as a Biomarker of Predisposition for COVID-19.Clinical nursing research · 2023Article
- ABO Blood Groups and Incidence of COVID-19 in the Mass Gathering Events in Borriana (Spain), March 2020: A Retrospective Cohort Study.Epidemiologia (Basel, Switzerland) · 2023Article
- Association of ABO blood types and clinical variables with COVID-19 infection severity in Libya.SAGE open medicine · 2023Article
- Clinical outcomes of COVID-19 in hemodialysis patients.Frontiers in medicine · 2023Article
- Association of ABO blood groups with ovarian reserve: a retrospective cohort study in Chinese Han women younger than 40 years with infertility.Journal of ovarian research · 2022Article
- Association between ABO blood groups and the risk of infection with SARS-CoV-2 in Iraq.The Journal of international medical research · 2022Article
- Association of ABO blood group with in-hospital adverse outcome and long term persistent symptoms of COVID-19 infection: A single-center longitudinal observational study.Health science reports · 2022Article
- Article
- COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis.F1000Research · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe SARS-CoV-2 pandemic has been affecting the health and economic, as well as social, life of the entire globe since the end of 2019. The virus causes COVID-19, with a wide range of symptoms among the infected individuals, from asymptomatic infection to mortality. This, along with a high infection rate, prompted efforts to investigate the potential mechanisms of the different clinical manifestations caused by SARS-CoV-2 among the infected populations. HYPOTHESIS: One of the possible mechanisms that has been reported is the ABO blood system polymorphism. Indeed, one of the major proposed mechanisms is the presence of naturally occurring anti-A antibodies in individuals of groups O and B, which could be partially protective against SARS-CoV-2 virions. OBJECTIVE AND
methodThis article aimed to review the published data on the potential effect of the ABO blood group system on the susceptibility to COVID-19 and the disease progression and outcomes.
resultsThe reviewed data suggest that individuals of blood group A are at a higher risk of infection with SARS-CoV-2 and may develop severe COVID-19 outcomes, whereas blood group O is considered protective against the infection, to some extent. However, some of the available studies seem to have been influenced by unaccounted confounders and biases.
conclusionTherefore, further appropriately controlled studies are warranted to fully investigate the possible association between the ABO blood groups and COVID-19 susceptibility and severity.
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