Evidence map›Paper›PMID 34541334›Full record

ReviewHealth science reports2021

Great future or greedy venture: Precision medicine needs philosophy.

Fei Jiao, Ruoyu Guo, Jacques S Beckmann, Zhonghai Yan, Yun Yang, Jinxia Hu, Xin Wang, Shuyang Xie

Abstract readReview
In one paragraph

Review in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Theorizing epidemiology, the stories bodies tell, and embodied truths: a status update on contending 21International journal of social determinants of health and health services · 2024
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fei JiaoDepartment of Biochemistry and Molecular Biology Binzhou Medical University Yantai China.
Ruoyu GuoDepartment of Biochemistry and Molecular Biology Binzhou Medical University Yantai China.
Jacques S BeckmannFaculty of Biology and Medicine University of Lausanne Lausanne Switzerland.ORCID https://orcid.org/0000-0002-9741-1900
Zhonghai YanDepartment of Medicine, College of Physicians and Surgeons Columbia University New York New York USA.
Yun YangDepartment of Biochemistry and Molecular Biology Binzhou Medical University Yantai China.
Jinxia HuDepartment of Biochemistry and Molecular Biology Binzhou Medical University Yantai China.
Xin WangDepartment of Clinical Laboratory & Center of Health Service Training 970 Hospital of the PLA Joint Logistic Support Force Yantai China.
Shuyang XieDepartment of Biochemistry and Molecular Biology Binzhou Medical University Yantai China.ORCID https://orcid.org/0000-0002-8090-2180

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOver the past decade, we have witnessed the initiation and implementation of precision medicine (PM), a discipline that promises to individualize and personalize medical management and treatment, rendering them ultimately more precise and effective. Despite of the continuing advances and numerous clinical applications, the potential of PM remains highly controversial, sparking heated debates about its future.

methodThe present article reviews the philosophical issues and practical challenges that are critical to the feasibility and implementation of PM. OUTCOME: The explanation and argument about the relations between PM and computability, uncertainty as well as complexity, show that key foundational assumptions of PM might not be fully validated.

conclusionThe present analysis suggests that our current understanding of PM is probably oversimplified and too superficial. More efforts are needed to realize the hope that PM has elicited, rather than make the term just as a hype.

Indexed as

biomarkercancerdatamodelprecision medicinesystem

Identifiers

PMID34541334
PMCPMC8439431

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.