ArticleSurgery journal (New York, N.Y.)2021
Prospective Comparative Observational Study of Safety and Efficacy of Topical Ozone Gas Therapy in Healing of Diabetic Foot Ulcers versus Only Conventional Wound Management.
Article in Surgery journal (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mechanism and clinical application of ozone therapy in treating skin ulcer diseases.Medical gas research · 2026Pooled it
- Effect of Ozone Therapy on Diabetes-related Foot Ulcer Outcomes: A Systematic Review and Meta-analysis.Current pharmaceutical design · 2024Pooled it
- Ozonized Sunflower Oil: Standardization and Mechanisms of the Antimicrobial Effect.International journal of molecular sciences · 2025Article
- Evaluating the therapeutic efficacy of ozone liquid dressing in healing wounds associated with bullous pemphigoid.Scientific reports · 2025Article
- Impact of ozone concentration on the treatment effectiveness of diabetic foot syndrome: a pilot single-centre study.Postepy dermatologii i alergologii · 2024Article
- Hypochlorous acid in a double formulation (liquid plus gel) is a key prognostic factor for healing and absence of infection in chronic ulcers. A nonrandomized concurrent treatment study.Health science reports · 2023Article
- Use of Ozone Therapy in Diabetic Foot Ulcers.Journal of personalized medicine · 2023Review
- Ozone therapy for skin diseases: Cellular and molecular mechanisms.International wound journal · 2023Review
- Evaluation of the healing potential of short-term ozone therapy for the treatment of diabetic foot ulcers.Frontiers in endocrinology · 2023Article
- Ozone therapy as a novel complementary therapeutic approach in refractory idiopathic granulomatous mastitis.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of diabetic foot ulcers (DFUs) in India is 11.6%. DFU accounts for major cost expenditure, morbidity, and mortality. 1 Ozone gas has antimicrobial and antioxidant properties. We studied efficacy of topical ozone gas therapy in promoting healing of DFU. This is an observational comparative cohort study,
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.