Evidence map›Paper›PMID 34541174›Full record

ArticleBio-protocol2017

Establishment of a Human Cell Line Persistently Infected with Sendai Virus.

Christopher Coakley, Cara Peter, Stephanie Fabry, Saurabh Chattopadhyay

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher CoakleyDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, USA.
Cara PeterDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, USA.
Stephanie FabryDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, USA.
Saurabh ChattopadhyayDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, USA.
University of Toledo · US

Funding

American Heart Association-American Stroke Association 15SDG25090212
6 · The paper itself

Abstract

Interferon regulatory transcription factor 3 (IRF3) is a transcription factor that upon activation by virus infection promotes the synthesis of antiviral genes, such as the interferons (Hiscott, 2007). In addition to inducing genes, IRF3 triggers antiviral apoptosis by RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA), which is independent of its transcriptional activity. RIPA protects against lethal virus infection in cells and mice ( Chattopadhyay

Indexed as

ApoptosisIRF3P2.1PersistenceSendai virus

Identifiers

PMID34541174
PMCPMC8413619
OpenAlexW2753766955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.