Evidence map›Paper›PMID 34541016›Full record

ArticleOrthopaedic journal of sports medicine2021

Anterior Cruciate Ligament Reconstruction With Concomitant Meniscal Repair: Is Graft Choice Predictive of Meniscal Repair Success?

Hytham S Salem, Laura J Huston, Alexander Zajichek, Eric C McCarty, Armando F Vidal, Jonathan T Bravman, Kurt P Spindler, Rachel M Frank, MOON Knee Group, Annunziato Amendola and 10 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00463099 (Prognosis and Predictors of ACL Reconstruction - A Multicenter Cohort Study), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00463099 active not recruitingnot on this map

Prognosis and Predictors of ACL Reconstruction - A Multicenter Cohort Study

TypeobservationalSponsorVanderbilt University Medical CenterRan2002 to 2028Enrolled3,294ConditionsRupture of Anterior Cruciate Ligament
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Anterior Cruciate Ligament Tears among Football Players.Current reviews in musculoskeletal medicine · 2025
    Review
  7. Review
  8. Return to sport rate following sports trauma-related delayed bucket-handle meniscus repair with concomitant ACL reconstruction.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Hytham S SalemCU Sports Medicine, Boulder, Colorado, USA.
Laura J HustonDepartment of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Alexander ZajichekDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Eric C McCartyCU Sports Medicine, Boulder, Colorado, USA.
Armando F VidalCU Sports Medicine, Boulder, Colorado, USA.
Jonathan T BravmanCU Sports Medicine, Boulder, Colorado, USA.
Kurt P SpindlerDepartment of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Rachel M FrankCU Sports Medicine, Boulder, Colorado, USA.
MOON Knee Group
Annunziato AmendolaCU Sports Medicine, Boulder, Colorado, USA.
Jack T AndrishCU Sports Medicine, Boulder, Colorado, USA.
Robert H BrophyCU Sports Medicine, Boulder, Colorado, USA.
Morgan H JonesCU Sports Medicine, Boulder, Colorado, USA.
Christopher C KaedingCU Sports Medicine, Boulder, Colorado, USA.
Robert G MarxCU Sports Medicine, Boulder, Colorado, USA.
Matthew J MatavaCU Sports Medicine, Boulder, Colorado, USA.
Richard D ParkerCU Sports Medicine, Boulder, Colorado, USA.
Michelle L WolcottCU Sports Medicine, Boulder, Colorado, USA.
Brian R WolfCU Sports Medicine, Boulder, Colorado, USA.
Rick W WrightCU Sports Medicine, Boulder, Colorado, USA.
Cleveland Clinic · USBoulder Institute for Sports Medicine · USVanderbilt University Medical Center · US

Funding

Prognosis and Predictors of ACL Reconstruction: A Multicenter Cohort StudyR01AR053684 · NIAMS · VANDERBILT UNIVERSITY · PI SPINDLER, KURT PAUL · 2006 to 2020
$8.3M
Meniscus status and activity level after ACLK23AR066133 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI JONES, MORGAN HERANCOURT · 2015 to 2019
$745k
NIAMS NIH HHS K23 AR066133NIAMS NIH HHS R01 AR053684
6 · The paper itself

Abstract

backgroundWhen meniscal repair is performed during anterior cruciate ligament (ACL) reconstruction (ACLR), the effect of ACL graft type on meniscal repair outcomes is unclear. HYPOTHESIS: The authors hypothesized that meniscal repairs would fail at the lowest rate when concomitant ACLR was performed with bone--patellar tendon--bone (BTB) autograft. STUDY

designCohort study; Level of evidence, 3.

methodsPatients who underwent meniscal repair at primary ACLR were identified from a longitudinal, prospective cohort. Meniscal repair failures, defined as any subsequent surgical procedure addressing the meniscus, were identified. A logistic regression model was built to assess the association of graft type, patient-specific factors, baseline Marx activity rating score, and meniscal repair location (medial or lateral) with repair failure at 6-year follow-up.

resultsA total of 646 patients were included. Grafts used included BTB autograft (55.7%), soft tissue autograft (33.9%), and various allografts (10.4%). We identified 101 patients (15.6%) with a documented meniscal repair failure. Failure occurred in 74 of 420 (17.6%) isolated medial meniscal repairs, 15 of 187 (8%) isolated lateral meniscal repairs, and 12 of 39 (30.7%) of combined medial and lateral meniscal repairs. Meniscal repair failure occurred in 13.9% of patients with BTB autografts, 17.4% of patients with soft tissue autografts, and 19.4% of patients with allografts. The odds of failure within 6 years of index surgery were increased more than 2-fold with allograft versus BTB autograft (odds ratio = 2.34 [95% confidence interval, 1.12-4.92];

conclusionMeniscal repair location (medial vs lateral) and baseline activity level were the main drivers of meniscal repair outcomes. Graft type was ranked third, demonstrating that meniscal repairs performed with allograft were 2.3 times more likely to fail compared with BTB autograft. There was no significant difference in failure rates between BTB versus soft tissue autografts. REGISTRATION: NCT00463099 (ClinicalTrials.gov identifier).

Indexed as

ACL reconstructionallograftautograftmeniscal repair

Identifiers

PMID34541016
PMCPMC8445540
OpenAlexW3199408765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.