Evidence map›Paper›PMID 34540996›Full record

ArticleBioMed research international2021

Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells.

Naoko Okada, Tetsuya Kawakita, Masataka Ito, Kazuo Tsubota

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Aquaporins in Glandular Secretion.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Naoko OkadaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Tetsuya KawakitaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3882-9052
Masataka ItoDepartment of Developmental Anatomy and Regenerative Biology, National Defense Medical College, Tokorozawa, Japan.
Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8874-7111
Keio University · JPNational Defense Medical College · JPNihon Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporins (AQPs) are proteins that selectively transport water across the cell membrane. Although AQPs play important roles in secretion in the lacrimal gland, the expression and localization of AQPs have not been clarified yet. In the current study, we investigated the expression pattern of AQP family members in the murine lacrimal gland during development. Lacrimal gland tissues were harvested from E13.5 and E17.5 murine embryos and from mice 8 weeks of age (adults). Corneal and conjunctival tissues from the latter served as controls. Total RNA was isolated and analyzed for the expression of AQP family members using qPCR. The localization of AQPs in the adult lacrimal gland in adult murine lacrimal glands was also analyzed. Expression of

Indexed as

Age FactorsAnimalsAquaporinsCell MembraneConjunctivaCorneaEpithelial CellsFemaleGene ExpressionLacrimal ApparatusMaleMiceMice, Inbred C57BLRNA, MessengerTranscriptomeAqp9 protein, mouseaquaporin 8AquaporinsRNA, Messenger

Identifiers

PMID34540996
PMCPMC8445729
OpenAlexW3196732002

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.