Evidence map›Paper›PMID 34540924›Full record

ReviewFrontiers in cardiovascular medicine2021

Optimizing Outcomes in Cardiac Rehabilitation: The Importance of Exercise Intensity.

Jenna L Taylor, Amanda R Bonikowske, Thomas P Olson

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06919237 (Chronic Adaptations in Cardiovagal Modulation and Cardiorespiratory Fitness in Patients With Coronary Artery Disease to a 12-week Heart Rate Variability-guided Training vs Traditional Aerobic Prescription Program), which is not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
20.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06919237 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Chronic Adaptations in Cardiovagal Modulation and Cardiorespiratory Fitness in Patients With Coronary Artery Disease to a 12-week Heart Rate Variability-guided Training vs Traditional Aerobic Prescription Program: Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorFaculdade de Motricidade HumanaRan2025 to 2028Enrolled48ConditionsCoronary Arterial Disease (CAD)ArmsHIIT Intervention, MICT Intervention, HRV-Guided Intervention
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.

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  20. Impact of Body Composition on Peak Oxygen Uptake After Cardiac Rehabilitation.medRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jenna L TaylorDivision of Preventative Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Amanda R BonikowskeDivision of Preventative Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Thomas P OlsonDivision of Preventative Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

Improving Cardiac Rehabilitation outcomes through mobile case management (iCARE)R01NR018832 · NINR · MAYO CLINIC ROCHESTER · PI OLSON, THOMAS PATRICK · 2020 to 2024
$2.7M
NINR NIH HHS R01 NR018832
6 · The paper itself

Abstract

Exercise based cardiac rehabilitation (CR) is recognized internationally as a class 1 clinical practice recommendation for patients with select cardiovascular diseases and heart failure with reduced ejection fraction. Over the past decade, several meta-analyses have generated debate regarding the effectiveness of exercise-based CR for reducing all-cause and cardiovascular mortality. A common theme highlighted in these meta-analyses is the heterogeneity and/or lack of detail regarding exercise prescription methodology within CR programs. Currently there is no international consensus on exercise prescription for CR, and exercise intensity recommendations vary considerably between countries from light-moderate intensity to moderate intensity to moderate-vigorous intensity. As cardiorespiratory fitness [peak oxygen uptake (VO

Indexed as

cardiorespiratory fitnesscardiovascular diseasecoronary artery diseaseexercise prescriptionheart failureinterval trainingpeak oxygen consumptionprogression

Identifiers

PMID34540924
PMCPMC8446279
OpenAlexW3196565261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.