Evidence map›Paper›PMID 34540831›Full record

ReviewFrontiers in cell and developmental biology2021

Human Embryos, Induced Pluripotent Stem Cells, and Organoids: Models to Assess the Effects of Environmental Plastic Pollution.

Dragana Miloradovic, Dragica Pavlovic, Marina Gazdic Jankovic, Sandra Nikolic, Milos Papic, Nevena Milivojevic, Miodrag Stojkovic, Biljana Ljujic

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dragana MiloradovicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Dragica PavlovicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Marina Gazdic JankovicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Sandra NikolicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Milos PapicDepartment of Dentistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Nevena MilivojevicLaboratory for Bioengineering, Department of Science, Institute for Information Technologies, University of Kragujevac, Kragujevac, Serbia.
Miodrag StojkovicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Biljana LjujicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For a long time, animal models were used to mimic human biology and diseases. However, animal models are not an ideal solution due to numerous interspecies differences between humans and animals. New technologies, such as human-induced pluripotent stem cells and three-dimensional (3D) cultures such as organoids, represent promising solutions for replacing, refining, and reducing animal models. The capacity of organoids to differentiate, self-organize, and form specific, complex, biologically suitable structures makes them excellent

Indexed as

bioinformaticsdrug screeningearly developmentenvironmental pollutionmodel diseaseorganoids

Identifiers

PMID34540831
PMCPMC8446652

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.