Evidence map›Paper›PMID 34540817›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Mechano-Hypoxia Conditioning of Engineered Human Meniscus.

Alexander R A Szojka, David Xinzheyang Li, Malou E J Sopcak, Zhiyao Ma, Melanie Kunze, Aillette Mulet-Sierra, Samer M Adeeb, Lindsey Westover, Nadr M Jomha, Adetola B Adesida

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Molecular Biology of Meniscal Healing: A Narrative Review.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Engineered Human Meniscus in Modeling Sex Differences of Knee OsteoarthritisFrontiers in bioengineering and biotechnology · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alexander R A SzojkaDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
David Xinzheyang LiDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Malou E J SopcakDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Zhiyao MaDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Melanie KunzeDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Aillette Mulet-SierraDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Samer M AdeebDepartment of Civil and Environmental Engineering, Faculty of Engineering, University of Alberta, Edmonton, AB, Canada.
Lindsey WestoverDepartment of Mechanical Engineering, Faculty of Engineering, University of Alberta, Edmonton, AB, Canada.
Nadr M JomhaDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Adetola B AdesidaDepartment of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meniscus fibrochondrocytes (MFCs) experience simultaneous hypoxia and mechanical loading in the knee joint. Experimental conditions based on these aspects of the native MFC environment may have promising applications in human meniscus tissue engineering. We hypothesized that

Indexed as

cyclic hydrostatic pressuredynamic compressionextracellular matrixhuman meniscushypoxiamechanical loadingtissue engineering

Identifiers

PMID34540817
PMCPMC8446439
OpenAlexW3196655630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.