ReviewFrontiers in pediatrics2021
All You Need Is Evidence: What We Know About Pneumonia in Children With Neuromuscular Diseases.
Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- A Novel Device for Pulmonary Expansion Under Simulated Healthy and Neuromuscular Conditions: A Bench Simulation Study.Medical devices (Auckland, N.Z.) · 2026Article
- Managing Cough in Pediatric Neuromuscular Disorders: Lung Function and Care Strategies.Children (Basel, Switzerland) · 2025Review
- The long-term efficacy of nusinersen on respiratory functions in children with symptomatic spinal muscular atrophy type 1.Turkish journal of medical sciences · 2025Article
- Diagnostic approach to the etiology of recurrent pneumonia in children.Pediatric pulmonology · 2024Article
- Respiratory morbidity in patients with spinal muscular atrophy-a changing world in the light of disease-modifying therapies.Frontiers in pediatrics · 2024Review
- Clinical Characteristics and Outcome of MDR/XDR Bacterial Infections in a Neuromuscular Semi-Intensive/Sub-Intensive Care Unit.Antibiotics (Basel, Switzerland) · 2022Article
- Lower Respiratory Tract Infections in Pediatric Patients with Severe Neurological Impairments: Clinical Observations and Perspectives in a Palliative Care Unit.Children (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuromuscular diseases may involve all major respiratory muscles groups including inspiratory, expiratory, and bulbar muscles. Respiratory complications are the major cause of morbidity and mortality. Pneumonia represents a frequent cause of morbidity in children with neuromuscular disease. The aim of this review is to collect knowledge about pneumonia in children with neuromuscular diseases. Pneumonia usually follows viral respiratory infections of the upper respiratory tract, due to the combination of an increased amount of nasal and oral secretions and an impairment of the cough efficiency and of the clearance of secretions due to the muscle weakness, further compromised by the infection itself. The accumulation of bronchial secretions leads to atelectasis and promote bacterial infection. Moreover, dysfunction of swallowing mechanism exposes these children to the risk of developing aspiration pneumonia. However, etiology of viral and bacterial respiratory infection in these patients is still poorly studied.
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Registered trials
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