Evidence map›Paper›PMID 34540532›Full record

ArticleAdvanced materials interfaces2021

Dosage-dependent antimicrobial activity of DNA-histone microwebs against

Ting Yang, Shi Yang, Tasdiq Ahmed, Katherine Nguyen, Jinlong Yu, Xuejun Cao, Rui Zan, Xiaonong Zhang, Hao Shen, Meredith E Fay and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. EngineeringJournal of materials chemistry. B · 2023
    Article
  3. EngineeringbioRxiv : the preprint server for biology · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Ting YangState Key Laboratory of Bioreactor Engineering, Department of Bioengineering, East China University of Science and Technology, Shanghai 200237, China.
Shi YangState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Tasdiq AhmedWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
Katherine NguyenWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
Jinlong YuDepartment of Orthopedics, Shanghai No.6 People's hospital, Shanghai 200233, China.
Xuejun CaoState Key Laboratory of Bioreactor Engineering, Department of Bioengineering, East China University of Science and Technology, Shanghai 200237, China.
Rui ZanState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Xiaonong ZhangState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Hao ShenDepartment of Orthopedics, Shanghai No.6 People's hospital, Shanghai 200233, China.
Meredith E FayWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
Evelyn Kendall WilliamsWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
Wilbur A LamWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
J Scott VanEppsDepartment of Emergency Medicine, Michigan Center for Integrative Research in Critical Care, Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109 USA.
Shuichi TakayamaWallace H Coulter Department of Biomedical Engineering & Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA 30332 USA.
Yang SongState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Georgia Institute of Technology · USShanghai Jiao Tong University · CNPeople's Liberation Army 411 Hospital · CNEast China University of Science and Technology · CNUniversity of Michigan · US

Funding

Research Training Program Plan on Cell and Tissue Engineering (CTEng)T32GM008433 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 1991 to 2021
$7.1M
Microfluidic Tissue Engineering of Small Airway InjuriesR01HL136141 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI GROTBERG, JAMES BERNARD, NEMZEK, JEAN A · 2017 to 2020
$2.9M
Super-resolution visualization of histones and histone modifications on individual chromatin fibersR01GM123517 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI LIU, YIFAN, TAKAYAMA, SHUICHI · 2017 to 2020
$1.6M
NHLBI NIH HHS R01 HL136141NIGMS NIH HHS R01 GM123517NIGMS NIH HHS T32 GM008433
6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) is an antimicrobial cobweb-structured material produced by immune cells for clearance of pathogens in the body, but paradoxically associated with biofilm formation and exacerbated lung infections. To provide a better materials perspective on the pleiotropic roles played by NETs at diverse compositions/concentrations, a NETs-like material (called 'microwebs', abbreviated as μwebs) is synthesized for decoding the antimicrobial activity of NETs against

Indexed as

BiofilmBiomimeticsmicrowebsNeutrophil Extracellular TrapsS. aureus

Identifiers

PMID34540532
PMCPMC8447838
OpenAlexW3193364729

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.