Evidence map›Paper›PMID 34540477›Full record

ReviewCureus2021

Untreated Depression During Pregnancy and Its Effect on Pregnancy Outcomes: A Systematic Review.

Nasrin Jahan, Terry R Went, Waleed Sultan, Alisha Sapkota, Hajra Khurshid, Israa A Qureshi, Michael Alfonso

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 5 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 5 syntheses or guidelines pooled it, 149 citations in OpenAlex.

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  9. Prenatal loss of control eating and cardiovascular health: Extending prior findings.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Nasrin JahanPsychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Terry R WentMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Waleed SultanMedicine, Beni Suef University Faculty of Medicine, Beni Suef, EGY.
Alisha SapkotaPsychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Hajra KhurshidPsychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Israa A QureshiInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Michael AlfonsoSchool of Medicine, Universidad del Rosario, Bogota, COL.
Universidad del Rosario · COBeni-Suef University · EGCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · USHalifax Health Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is characterized by sad, irritated, or empty moods, as well as somatic and cognitive changes such as loss of concentration, anhedonia, hopelessness, loss of appetite, sleep disturbances, and suicidal ideation, all of which have a negative impact on an individual's ability to function. Depression that occurs during pregnancy is known as antenatal depression. The occurrence of depression during pregnancy and afterward is quite high. Women having a history of depression before pregnancy have a high probability of getting depression during pregnancy again. The purpose of the study is to review the effect of untreated depression during pregnancy on maternal and neonatal outcomes. The primary outcomes of this review were the identification of studies showing the relationship between untreated depression during the pregnancy indicated by depression measures and any associated adverse birth outcomes; specifically, low birth weight, small for gestational age, preterm birth, postpartum depression, and infant neurodevelopmental outcome. We reviewed 20 population-based contemporary cohort studies with a range of populations from 54 to 194,494, all of them representing the population of gestational age located in multiple jurisdictions. It was found that maternal depression during pregnancy has a positive association with preterm birth, small for gestational age, stillbirth, low birth weight, and maternal morbidity including perinatal complications, increased operative delivery, and postpartum depression. To prevent these adverse outcomes, depression should be screened, monitored, and managed appropriately keeping risk-benefit in consideration.

Indexed as

maternal depressionmaternal outcomesneonatal outcomespregnancy outcomesuntreated depression

Identifiers

PMID34540477
PMCPMC8448270
OpenAlexW3195334668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.