Evidence map›Paper›PMID 34540338›Full record

ArticleACS catalysis2021

Structural and biochemical studies enlighten the unspecific peroxygenase from Hypoxylon sp. EC38 as an efficient oxidative biocatalyst.

Laura Rotilio, Alexander Swoboda, Katharina Ebner, Claudia Rinnofner, Anton Glieder, Wolfgang Kroutil, Andrea Mattevi

Open access · hybridAbstract read
In one paragraph

Article in ACS catalysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Empowering Precision C-H Functionalization: Advances in Peroxygenase Engineering.Angewandte Chemie (International ed. in English) · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Rapid screening system to identify unspecific peroxygenase activity.Clinical hemorheology and microcirculation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Laura RotilioDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Alexander SwobodaAustrian Centre of Industrial Biotechnology, c/o Institute of Chemistry, University of Graz, Heinrichstraße 28, 8010 Graz, Austria.
Katharina EbnerInstitute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.
Claudia RinnofnerInstitute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.
Anton GliederInstitute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010 Graz, Austria.
Wolfgang KroutilAustrian Centre of Industrial Biotechnology, c/o Institute of Chemistry, University of Graz, Heinrichstraße 28, 8010 Graz, Austria.
Andrea MatteviDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Institute of Molecular Biotechnology · ATUniversity of Graz · ATUniversity of Pavia · IT

Funding

Austrian Science Fund FWF P 18537
6 · The paper itself

Abstract

Unspecific peroxygenases (UPO) are glycosylated fungal enzymes that can selectively oxidize C-H bonds. UPOs employ hydrogen peroxide as oxygen donor and reductant. With such an easy-to-handle co-substrate and without the need of a reducing agent, UPOs are emerging as convenient oxidative biocatalysts. Here, an unspecific peroxygenase from

Indexed as

biocatalytic oxidationmonooxygenaseperoxygenaseprotein tunnelssubstrate recognition

Identifiers

PMID34540338
PMCPMC7611678
OpenAlexW3198293894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.