Evidence map›Paper›PMID 34540308›Full record

ArticleWestern Pacific surveillance and response journal : WPSAR

Estimating the national burden of hospitalizations for influenza-associated severe acute respiratory infection in the Lao People's Democratic Republic, 2016.

Bouaphanh Khamphaphongphane, May Chiew, Joshua A Mott, Sombandith Khamphanoulath, Viengphone Khanthamaly, Keooudomphone Vilivong, Thongchanh Sisouk, Leila Bell, Erica Dueger, Sheena Sullivan and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Western Pacific surveillance and response journal : WPSAR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 5 countries.

Bouaphanh KhamphaphongphaneNational Center for Laboratory and Epidemiology, Vientiane, Lao People's Democratic Republic.
May ChiewWHO Health Emergencies Programme, World Health Organization, Vientiane, Lao People's Democratic Republic.
Joshua A MottInfluenza Division, Thailand Regional Influenza Program, United States Centers for Disease Control and Prevention, Nonthaburi, Thailand.
Sombandith KhamphanoulathNational Center for Laboratory and Epidemiology, Vientiane, Lao People's Democratic Republic.
Viengphone KhanthamalyInfluenza Division, United States Centers for Disease Control and Prevention, US Embassy, Vientiane, Lao People's Democratic Republic.
Keooudomphone VilivongNational Center for Laboratory and Epidemiology, Vientiane, Lao People's Democratic Republic.
Thongchanh SisoukNational Center for Laboratory and Epidemiology, Vientiane, Lao People's Democratic Republic.
Leila BellHealth Emergency Information and Risk Assessment, WHO Health Emergencies Programme, World Health Organization, Regional Office for the Western Pacific, Manila, Philippines.
Erica DuegerInfectious Hazards Management, WHO Health Emergencies Programme, World Health Organization, Regional Office for the Western Pacific, Manila, Philippines.
Sheena SullivanWHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Melbourne, and the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.
Angela Daniella IulianoInfluenza Division, United States Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Reiko TsuyuokaWHO Health Emergencies Programme, World Health Organization, Vientiane, Lao People's Democratic Republic.
Onechanh KeosavanhNational Center for Laboratory and Epidemiology, Vientiane, Lao People's Democratic Republic.
Centers for Disease Control and Prevention · USThe Royal Melbourne Hospital · AUWorld Health Organization - Pakistan · PKWorld Health Organization Regional Office for the Western Pacific · PH

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveEstimates of the burden of influenza are needed to inform prevention and control activities for seasonal influenza, including to support the development of appropriate vaccination policies. We used sentinel surveillance data on severe acute respiratory infection (SARI) to estimate the burden of influenza-associated hospitalizations in the Lao People's Democratic Republic.

methodsUsing methods developed by the World Health Organization, we combined data from hospital logbook reviews with epidemiological and virological data from influenza surveillance from 1 January to 31 December 2016 in defined catchment areas for two sentinel sites (Champasack and Luang Prabang provincial hospitals) to derive population-based estimates of influenza-associated SARI hospitalization rates. Hospitalization rates by age group were then applied to national age-specific population estimates using 2015 census data.

resultsWe estimated the overall influenza-associated SARI hospitalization rate to be 48/100 000 population (95% confidence interval [CI]: 44-51) or 3097 admissions (95% CI: 2881-3313). SARI hospitalization rates were estimated to be as low as 40/100 000 population (95% CI: 37-43) and as high as 92/100 000 population (95% CI: 87-98) after accounting for SARI patient underascertainment in hospital logbooks. Influenza-associated SARI hospitalization rates were highest in children aged < 5 years (219; 95% CI: 198-241) and persons aged DISCUSSION: Our findings have identified age groups at higher risk for influenza-associated SARI hospitalization, which will support policy decisions for influenza prevention and control strategies, including for vaccination. Further work is needed to estimate the burdens of outpatient influenza and influenza in specific high-risk subpopulations.

Indexed as

Influenza, HumanRespiratory Tract InfectionsChildHospitalizationHumansInfantRisk FactorsSentinel Surveillance

Identifiers

PMID34540308
PMCPMC8421749
OpenAlexW3199509849

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.