ArticleAnnals of medicine and surgery (2012)2021
Biliary infection; distribution of species and antibiogram study.
Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06314399 (Predictive Factors Associated with Bile Culture Positivity and PhenotypiCal AntIbiogram Resistance Patterns in Patients Taken to LaparOscopic Cholecystectomy), which is not on this map. Cited by 15 papers.
What it found
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The trial behind it
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Predictive Factors Associated with Bile Culture Positivity and PhenotypiCal AntIbiogram Resistance Patterns in Patients Taken to LaparOscopic Cholecystectomy (BACILO): a Protocol for a Prediction Model Study
Who cites it
15 citing papers in PubMed.
- Biliary Microbiota in Health and Disease: Clinical Implications in Lithiasis, Infection, and Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2026Review
- Acute Calculous Cholangitis: Causative Aerobic Bacteria and Antibiotic Susceptibility Patterns from a Retrospective Multicenter Study in Vietnam.Life (Basel, Switzerland) · 2026Article
- GenusMicroorganisms · 2026Article
- The Microbiological Spectrum and Antibiotic Resistance in Acute Acalculous and Calculous Cholecystitis: A Seven-Year Study in a Tertiary Center.Medicina (Kaunas, Lithuania) · 2025Article
- Microbial Profile and Antibiotic Resistance Patterns in Bile Aspirates from Patients with Acute Cholangitis: A Multicenter International Study.Antibiotics (Basel, Switzerland) · 2025Article
- Identification and characterization of bile microbiota in patients with biliary obstructive diseases using next-generation sequencing of 16S rRNA and ITS.Frontiers in cellular and infection microbiology · 2025Article
- Prospective insights into acute cholangitis: microbial patterns, resistance, risk factors, and outcomes.Gastroenterology and hepatology from bed to bench · 2025Article
- Article
- Updates on Antibiotic Regimens in Acute Cholecystitis.Medicina (Kaunas, Lithuania) · 2024Review
- Altered microbiome of serum exosomes in patients with acute and chronic cholecystitis.BMC microbiology · 2024Article
- Comparative Analysis of Microbial Species and Multidrug Resistance Patterns in Acute Cholangitis Patients with Cholecystectomy: A Single-Center Study.Diseases (Basel, Switzerland) · 2024Article
- Temporal Shifts in Etiological Agents and Antibiotic Resistance Patterns of Biliary Tract Infections in Sichuan Province, China (2017-2023).Infection and drug resistance · 2024Article
- The distribution and antibiotic-resistant characteristics and risk factors of pathogens associated with clinical biliary tract infection in humans.Frontiers in microbiology · 2024Article
- A Six-Year Retrospective Study of Microbiological Characteristics and Antimicrobial Resistance in Specimens from a Tertiary Hospital's Surgical Ward.Antibiotics (Basel, Switzerland) · 2023Article
- Implications of Type 2 Diabetes Mellitus in Patients with Acute Cholangitis: A Systematic Review of Current Literature.Healthcare (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiliary infections like cholecystitis and cholangitis are common and could be life threatening if treated inappropriate. Prescribing antibiotics is the key to control such infections. Occurrence of bacterial resistance to antibiotics is highly probable and should be continuously monitored. This study aimed to re-evaluate bacterial species distribution and their interaction to antibiotics in biliary infections.
methodTotal 2288 patients who were diagnosed as whether acute or chronic cholecystitis with/without concurrent cholangitis enrolled in this cohort study. All were candidate for cholecystectomy operation. In the theatre a sterile bile sample was aspirated from the gallbladder as early as the organ was exposed. Analysis was performed on culture and antibiogram results.
resultsFinally 492 (21.5%) microorganism growth was seen in all culture environments. Bacterial colonization was most common in cholangitis (63.8%) which followed by acute (26%) and chronic (10.9%) cholecystitis respectively (
conclusionCephalosporins as an empirical treatment for biliary infections is not suitable. Aminoglycosides including amikacin and gentamycin are costly beneficial as the first line for empirical antibiotic therapy in selected patients because of their good bacterial sensitivity and low expenses. Imipenem should remain for multidrug resistance species.
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