Evidence map›Paper›PMID 34540175›Full record

ArticleIranian journal of microbiology2021

Therapeutic effects, immunogenicity and cytotoxicity of a cell penetrating peptide-peptide nucleic acid conjugate against

Narges Nodeh Farahani, Behrooz Sadeghi Kalani, Seyed Hamidreza Monavari, Shiva Mirkalantari, Fatemeh Montazer, Mohammad Sholeh, Zahra Javanmard, Gholamreza Irajian

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. MicroRNA-Mediated Regulatory Networks inBiochemistry research international · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Narges Nodeh FarahaniMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Behrooz Sadeghi KalaniDepartment of Medical Microbiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Seyed Hamidreza MonavariDepartment of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Shiva MirkalantariMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Fatemeh MontazerFiroozabadi Clinical Research and Development Unit (FACRDU), Iran university of Medical Sciences (IUMS), Tehran, Iran.
Mohammad SholehMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Zahra JavanmardMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Gholamreza IrajianMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Biotechnology Research Center · IRIran University of Medical Sciences · IRMedical University of Ilam · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesMATERIALS AND

methodsIn this experimental study, a cell-penetrating peptide-conjugated peptide nucleic acid (CPP-PNA) was used to target the

resultsOur analysis showed that

conclusionThese results suggest the effectiveness of CPP-PNA in targeting CagA for various research and therapeutic purposes, offering a potential antisense therapy against

Indexed as

cag ACytotoxicityHelicobacter pyloriImmunogenicityPeptide nucleic acid

Identifiers

PMID34540175
PMCPMC8416595
OpenAlexW3166317559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.