Evidence map›Paper›PMID 34540144›Full record

ArticleUpsala journal of medical sciences2021

Mortality in Eosinophilic Esophagitis - a nationwide, population-based matched cohort study from 2005 to 2017.

Lovisa Röjler, John J Garber, Bjorn Roelstraete, Marjorie M Walker, Jonas F Ludvigsson

Abstract read
In one paragraph

Article in Upsala journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Eosinophilic gastrointestinal diseases.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. How should we interpret the data of eosinophilic esophagitis patients from an academic institution?JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  8. Eosinophilic Esophagitis-What Do We Know So Far?Journal of clinical medicine · 2023
    Review
  9. Increasing incidence of eosinophilic esophagitis in Sweden: a nationwide population study.Esophagus : official journal of the Japan Esophageal Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lovisa RöjlerDepartment of Pediatrics, Örebro University Hospital, Sweden.
John J GarberGastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA.
Bjorn RoelstraeteDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Marjorie M WalkerDepartment Anatomical Pathology University of Newcastle Faculty of Health and Medicine School of Medicine and Public Health Callaghan, NSW, Australia.
Jonas F LudvigssonDepartment of Pediatrics, Örebro University Hospital, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of knowledge about mortality in eosinophilic esophagitis (EoE). Therefore, this study aimed to examine the mortality in EoE.

methodsA nationwide, population-based matched cohort study was conducted of all EoE patients in Sweden diagnosed between July 2005 and December 2017. Individuals with EoE (

resultsThrough December 2017, 34 deaths were confirmed in EoE patients (4.60 per 1,000 person-years) compared with 165 in reference individuals (4.57 per 1,000 person-years). This rate corresponds to an aHR of 0.97 (95% CI = 0.67-1.40). HRs were similar in males (aHR = 1.00 [0.66-1.51]) and females (aHR = 0.92 [0.38-2.18]). We observed no increased risk in mortality due to esophageal or other gastrointestinal cancers in patients with EoE (aHR = 1.02 [0.51-2.02]).Mortality was similar in EoE patients and their siblings (aHR = 0.91 [0.44-1.85]).

conclusionIn this nationwide, population-based matched cohort study in Sweden, there was no increased risk of death in patients with EoE compared with their siblings and the general population.

Indexed as

Eosinophilic EsophagitisCohort StudiesFemaleHumansMaleProportional Hazards ModelsSwedencancerdeatheosinophilic esophagitismortalitypopulation-based

Identifiers

PMID34540144
PMCPMC8431988

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.