A study on the esophageal dynamics in patients with gastroesophageal reflux disease and with refractory cough undergoing esophageal high-resolution manometry.

Yinghui Zhang, Qiong Chen, Lan Yang, Zhou Zhou, Xiaoshu Liu

Abstract read

In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Comparative efficacy of laparoscopic Dor and Nissen fundoplication for refractory gastroesophageal reflux disease.American journal of translational research · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yinghui ZhangDepartment of Gastroenterology and Hepatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu, China.

Qiong ChenDepartment of Gastroenterology and Hepatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu, China.

Lan YangDepartment of Gastroenterology and Hepatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu, China.

Zhou ZhouDepartment of Gastroenterology and Hepatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu, China.

Xiaoshu LiuDivision of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the esophageal dynamics in patients with gastroesophageal reflux disease (GERD) and with refractory cough while undergoing esophageal high-resolution manometry (HRM).

methodsA total of 32 patients with GERD and with refractory cough and 48 patients with GERD admitted to our hospital from February 2019 to July 2020 were assigned to the combined group and the GERD group, respectively, and 40 healthy volunteers were assigned to the healthy group. All the patients underwent HRM. The lower esophageal sphincter (LES) and the upper esophageal sphincter (UES) parameters, the types of peristalsis of the esophageal body, the esophageal body motility, the i relaxation of LES and UES incidence rates, and the esophageal body motility disorders were compared among the three groups.

resultsThe combined group and the GERD group had lower esophageal sphincter pressure (LESP) levels and lower 4-s integrated relaxation pressure (4 s IRP) levels, shorter lower esophageal sphincter lengths (LESL), and higher frequencies and longer durations of transient lower esophageal sphincter relaxation (TLESR) compared with the healthy group (

conclusionPatients with GERD and with refractory cough often also have esophageal body motility disorders, longer PB, elevated UESP levels, and lower DCI. HRM can be used to objectively evaluate the esophageal dynamics and to differentiate among diseases.

Indexed as

esophageal dynamicsesophageal high-resolution manometryGastroesophageal reflux diseaserefractory cough

Identifiers

PMID34540077

PMCPMC8430120

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.