Evidence map›Paper›PMID 34540031›Full record

ArticleAmerican journal of translational research2021

Analysis of optic disc and macular vascular density in patients with non-proliferative diabetic retinopathy.

Hong Li, Min Zheng

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hong LiDepartment of Ophthalmology, Dongying People's Hospital Shandong Province, China.
Min ZhengDepartment of Ophthalmology, Dongying People's Hospital Shandong Province, China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the vascular density of optic disc and macular area in patients with non-proliferative diabetic retinopathy (NPDR).

methodsThe medical records of 97 patients with NPDR who were hospitalized in our hospital from April 2019 to April 2020 were collected, and the patients were divided into mild/moderate group (n=44) and severe group (n=53). In addition, 38 cases of age- and gender-matched healthy individuals after the physical examination during the same period were included in the healthy control group. The general data were collected and the ocular basic and optical coherence tomography angiography were performed.

resultsCompared with the healthy control group, the best corrected visual acuity of patients with NPDR was decreased, the radial capillary density of the whole optic disc and its surrounding areas, all areas except the upper nasal side, and the shallow and deep capillary density of different macular areas witnessed an evident drop (

conclusionThe vascular density of the optic disc and macular area decreases in NPDR patients, which is closely related to the severity of the disease.

Indexed as

macularNon-proliferative diabetic retinopathyoptical coherence tomography angiographyoptic discvascular density

Identifiers

PMID34540031
PMCPMC8430068
OpenAlexW3200213861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.