Evidence map›Paper›PMID 34540029›Full record

ArticleAmerican journal of translational research2021

Analysis of risk factor for pediatric intensive care unit delirium in children: a case-control study.

Xiao-Hua Ge, Wan-Rui Wei, Tie-Nan Feng, Li-Li Xu, Ya-Qin Hu, Chang-Rong Yuan

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07365215 (Pediatric Delirium in Swedish PICUs), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07365215 completednot on this mapstarted 2023, after this paper: background citation

Pediatric Delirium in Swedish PICUs: Incidence, Risk Factors, and Validation of the Swedish Cornell Assessment of Pediatric Delirium (CAPD) Instrument.

Typeobservational_patient_registrySponsorUppsala UniversityRan2023 to 2025Enrolled676ConditionsPediatric Delirium, Pediatric Intensive Care, Risk Factors
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiao-Hua GeSchool of Nursing, Naval Medical University Shanghai, China.
Wan-Rui WeiSchool of Nursing, Shanghai Jiao Tong University Shanghai, China.
Tie-Nan FengClinical Research Institute, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Li-Li XuPediatric Intensive Care Unit, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai, China.
Ya-Qin HuPediatric Intensive Care Unit, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai, China.
Chang-Rong YuanSchool of Nursing, Naval Medical University Shanghai, China.
Shanghai Jiao Tong University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to survey the prevalence of delirium in the pediatric intensive care unit (PICU) and explore the associated risk factors.

designA retrospective case-control study.

settingTwo PICUs within a tertiary-A general hospital. PATIENTS: Patients aged from 1 month to 7 years who stayed in either PICU for at least 1 day were included.

methodsA total of 639 patients admitted to PICU of a tertiary-A general hospital from December 2018 to August 2019 were enrolled. Demographic, clinical, laboratory data and length of stay in the PICU were collected. The patients were screened twice a day with the Chinese version of Cornell Assessment of Pediatric Delirium (CAPD), and were divided into the delirium group and the non-delirium group. A risk factor analysis was conducted, with ICU pediatric delirium as primary outcome, by performing a multivariable logistic regression analysis.

resultsOf the 639 patients, the prevalence of ICU pediatric delirium was 31.30%. Of the 200 children with delirium across 3703 study days, 36% children were hyperactive, 41% were hypoactive, and 23% displayed the mixed type of delirium. Univariate analysis and multivariate logistic regression analysis showed that age, PRISM IV score (OR, 2.20; 95% CI, 1.42-3.41), hypoxia (OR, 2.69; 95% CI, 1.53-4.71), metabolic dis-function (OR, 3.73; 95% CI, 2.08-6.71), duration of infection (OR, 1.22; 95% CI, 1.10-1.36), and mechanical ventilation (OR, 3.78; 95% CI, 2.25-6.35) were statistically correlated with ICU pediatric delirium. The ROC curve analysis shows the combination CRP with duration of infection has good predictive performance.

conclusionsAge, PRISM IV score, ICU retention time, metabolic dis-function, duration of infection, hypoxia, CRP and mechanical ventilation were the independent risk factors for ICU pediatric delirium. We suggest that active preventive measures should be taken to reduce the occurrence of ICU pediatric delirium.

Indexed as

childrencritical caredeliriumPediatricrisk factor

Identifiers

PMID34540029
PMCPMC8430069
OpenAlexW3199453412

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.