Evidence map›Paper›PMID 34539810›Full record

ArticleFuture virology2021

Serum biochemical parameters as a surrogate marker for chest computed tomography in children with COVID-19.

Karuna M Das, Rajvir Singh, Sandeep Subramanya, Shreesh Kumar Ojha, Taleb Almansoori, Dilip Gokhale, Jamal Aldeen Alkoteesh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karuna M DasDepartment of Radiology, CMHS, UAEU, Al Ain, UAE.ORCID https://orcid.org/0000-0002-4703-5433
Rajvir SinghDepartment of Biostatistics, AIIMS, New Delhi, India.
Sandeep SubramanyaDepartment of Physiology, CMHS, UAEU, Al Ain, UAE.
Shreesh Kumar OjhaDepartment of Pharmacology, CMHS, UAEU, Al Ain, UAE.
Taleb AlmansooriDepartment of Radiology, CMHS, UAEU, Al Ain, UAE.
Dilip GokhaleDepartment of Radiology, Tawam Hospital, Al Ain, UAE.
Jamal Aldeen AlkoteeshDepartment of Radiology, Tawam Hospital, Al Ain, UAE.
All India Institute of Medical Sciences Raipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to investigate whether serum biochemical parameters can be used as a surrogate for chest computed tomography (CT) in the diagnosis of COVID-19 in pediatric patients. MATERIALS &

methodsWe evaluated potential associations between various serum biochemical markers and the COVID-reporting and data system (RADS) pneumonia grading system in 53 individuals with confirmed COVID-19.

resultsA total of 28 chest CT scans (52.8%) were abnormal. Patients with confirmed COVID-19 on CT showed a statistically significant increase in lactate dehydrogenase (186.4 ± 56.5 vs 228.4 ± 60.6; p = 0.01), which was significantly correlated with the COVID-RADS pneumonia grading system.

conclusionLactate dehydrogenase can be used as a surrogate marker for chest CT in children with COVID-19. This can reduce exposure to ionizing radiation during initial diagnostic procedures in children with suspected COVID-19 pneumonia.

Indexed as

Chest CTCOVID-19LDHserum ferritin

Identifiers

PMID34539810
PMCPMC8439343
OpenAlexW3197734335

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.